C₂₅H₂₆N₂OS

Base Information

• Chemical Name: C₂₅H₂₆N₂OS
• CAS No.: 289711-63-3
• Molecular Formula: C₂₅H₂₆N₂OS
• Molecular Weight: 402.56
• Mol file: 289711-63-3.mol

Synonyms:

Chemical Property of C₂₅H₂₆N₂OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₆N₂OS

There total 3 articles about C₂₅H₂₆N₂OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-49-0) → C25H26N2OS (289711-63-3)

Guidance literature:

With potassium hydroxide; In ethanol; for 8h; Heating;

DOI:10.1007/BF02251821

Reference yield:

1-isothiocyanato-4-methylbenzene (622-59-3) → C25H26N2OS (289711-63-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ethanol / 14 h / Heating

1.2: 78 percent / KOH / aq. ethanol / 5 h / Heating

2.1: 72 percent / KOH / ethanol / 8 h / Heating

With potassium hydroxide; In ethanol; 1.1: Addition / 1.2: Cyclization / 2.1: Alkylation;

DOI:10.1007/BF02251821

Reference yield:

4-amino-3-ethoxycarbonyl-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane) (221238-51-3) → C25H26N2OS (289711-63-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ethanol / 14 h / Heating

1.2: 78 percent / KOH / aq. ethanol / 5 h / Heating

2.1: 72 percent / KOH / ethanol / 8 h / Heating

With potassium hydroxide; In ethanol; 1.1: Addition / 1.2: Cyclization / 2.1: Alkylation;

DOI:10.1007/BF02251821

upstream raw materials:

4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

1-isothiocyanato-4-methylbenzene

4-amino-3-ethoxycarbonyl-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane)

Refernces