2,2-dichloro-N-(2-hydroxyphenyl)acetamide

Base Information

Chemical Name:2,2-dichloro-N-(2-hydroxyphenyl)acetamide
CAS No.:14676-36-9
Molecular Formula:C₈H₇Cl₂NO₂
Molecular Weight:220.055
Hs Code.:
DSSTox Substance ID:DTXSID701272704

Synonyms:2,2-dichloro-N-(2-hydroxyphenyl)acetamide;2-(dichloroacetamido)phenol;14676-36-9;SCHEMBL10339293;DTXSID701272704;AKOS001575484;SR-01000103730;SR-01000103730-1

Suppliers and Price of 2,2-dichloro-N-(2-hydroxyphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-dichloro-N-(2-hydroxyphenyl)acetamide

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:218.9853839
Heavy Atom Count:13
Complexity:187

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC(=O)C(Cl)Cl)O

Technology Process of 2,2-dichloro-N-(2-hydroxyphenyl)acetamide

There total 1 articles about 2,2-dichloro-N-(2-hydroxyphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 79-36-7
dichloroacethyl chloride

: 95-55-6
2-amino-phenol

: 14676-36-9
2-hydroxy-α,α-dichloroacetanilide

Guidance literature:: In diethyl ether; at 20 ℃; for 3h;
DOI:10.1021/jf051147i

Reference yield: 76.4%

: 14676-36-9
2-hydroxy-α,α-dichloroacetanilide

: 23520-34-5
Blepharigenin

Guidance literature:: With sodium hydrogencarbonate; In water; for 1.5h; Heating;

Reference yield:

: 14676-36-9
2-hydroxy-α,α-dichloroacetanilide

: 78958-15-3
2'-hydroxy-N-(2-hydroxyphenyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 0.2 M aq. NaHCO₃ / 0.17 h / Heating

2: NaBH₄ / methanol / Ambient temperature

With sodium tetrahydroborate; sodium hydrogencarbonate; In methanol;