D-glycero-L-talo-heptonic acid-4-lactone

Base Information

• Chemical Name: D-glycero-L-talo-heptonic acid-4-lactone
• CAS No.: 221129-03-9
• Molecular Formula: C₇H₁₂O₇
• Molecular Weight: 208.168
• Mol file: 221129-03-9.mol

Synonyms:

Chemical Property of D-glycero-L-talo-heptonic acid-4-lactone

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D-glycero-L-talo-heptonic acid-4-lactone

There total 4 articles about D-glycero-L-talo-heptonic acid-4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-glycero-L-talo-heptonic acid (882983-01-9) → D-glycero-L-talo-heptonic acid-4-lactone (221129-03-9)

Guidance literature:

With hydrogenchloride; water;

Reference yield:

(3aR,6R,6aR)-6-((4S,5R)-5-Hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-dihydro-furo[3,4-d][1,3]dioxol-4-one → D-glycero-L-talo-heptonic acid-4-lactone (221129-03-9)

Guidance literature:

With ion exchange resin (IR 120 H(+)); In water; for 1h; Yield given;

DOI:10.1055/s-1999-3384

Reference yield:

(4S,5R)-3,4-Dihydroxy-5-((1S,2R)-1,2,3-trihydroxy-propyl)-dihydro-furan-2-one (221129-02-8) → D-glycero-L-talo-heptonic acid-4-lactone (221129-03-9)

Guidance literature:

Multi-step reaction with 2 steps

1: TsOH / 22 h / Heating

2: ion exchange resin (IR 120 H(+)) / H₂O / 1 h

With ion exchange resin (IR 120 H(+)); toluene-4-sulfonic acid; In water;

DOI:10.1055/s-1999-3384

upstream raw materials:

D-glycero-L-talo-heptonic acid

(4S,5R)-3,4-Dihydroxy-5-((1S,2R)-1,2,3-trihydroxy-propyl)-dihydro-furan-2-one

L-gulose