Technology Process of c-2-methyl-2-((4-methylphenyl)sulfonyl)-r-1-cyclopentanol
There total 6 articles about c-2-methyl-2-((4-methylphenyl)sulfonyl)-r-1-cyclopentanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: NaOEt / ethanol / 1 h / Heating
2: m-chloroperoxybenzoic acid / CCl4 / 1.) 0 deg C, 2.) room temp., 5 h
3: 91 percent / Jones reagent / acetone / 1.) 0 deg C, 2.) room temp., 2 h
4: L-Selectride / tetrahydrofuran / 1.) -78 deg C, 2 h, 2.) room temp., 18 h
5: 1.) n-BuLi / 1.) THF, -78 deg C, 10 min, 2.) -78 deg C, 4 h
With
n-butyllithium; jones reagent; sodium ethanolate; L-Selectride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; tetrachloromethane; ethanol; acetone;
DOI:10.1021/jo00171a037
- Guidance literature:
-
Multi-step reaction with 4 steps
1: m-chloroperoxybenzoic acid / CCl4 / 1.) 0 deg C, 2.) room temp., 5 h
2: 91 percent / Jones reagent / acetone / 1.) 0 deg C, 2.) room temp., 2 h
3: L-Selectride / tetrahydrofuran / 1.) -78 deg C, 2 h, 2.) room temp., 18 h
4: 1.) n-BuLi / 1.) THF, -78 deg C, 10 min, 2.) -78 deg C, 4 h
With
n-butyllithium; jones reagent; L-Selectride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; tetrachloromethane; acetone;
DOI:10.1021/jo00171a037
- Guidance literature:
-
Multi-step reaction with 5 steps
1: NaOEt / ethanol / 1 h / Heating
2: m-chloroperoxybenzoic acid / CCl4 / 1.) 0 deg C, 2.) room temp., 5 h
3: 91 percent / Jones reagent / acetone / 1.) 0 deg C, 2.) room temp., 2 h
4: L-Selectride / tetrahydrofuran / 1.) -78 deg C, 2 h, 2.) room temp., 18 h
5: 1.) n-BuLi / 1.) THF, -78 deg C, 10 min, 2.) -78 deg C, 4 h
With
n-butyllithium; jones reagent; sodium ethanolate; L-Selectride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; tetrachloromethane; ethanol; acetone;
DOI:10.1021/jo00171a037
