2-(2-Chloro-5-methylphenoxy)acetohydrazide

Base Information

• Chemical Name: 2-(2-Chloro-5-methylphenoxy)acetohydrazide
• CAS No.: 588680-02-8
• Molecular Formula: C₉H₁₁ClN₂O₂
• Molecular Weight: 214.652
• DSSTox Substance ID: DTXSID001232523
• Mol file: 588680-02-8.mol

Synonyms:2-(2-chloro-5-methylphenoxy)acetohydrazide;588680-02-8;N-Amino-2-(2-chloro-5-methylphenoxy)ethanamide;Oprea1_360224;DTXSID001232523;BBL016834;MFCD00245635;STK435840;AKOS000305321;MS-7181;SB86089;CS-0315798;(2-chloro-5-methyl-phenoxy)-acetic acid hydrazide;2-(2-Chloro-5-methylphenoxy)acetic acid hydrazide

Chemical Property of 2-(2-Chloro-5-methylphenoxy)acetohydrazide

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 214.0509053
• Heavy Atom Count: 14
• Complexity: 201

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Chloro-5-methylphenoxy)acetohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)Cl)OCC(=O)NN

Technology Process of 2-(2-Chloro-5-methylphenoxy)acetohydrazide

There total 1 articles about 2-(2-Chloro-5-methylphenoxy)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-chloro-5-methylphenoxy)acetic acid (1556-00-9) → (2-chloro-5-methyl-phenoxy)-acetic acid hydrazide (588680-02-8)

Guidance literature:

With hydrazine hydrate; sulfuric acid; In methanol; for 25h; Heating;

DOI:10.1211/0022357011775307

Reference yield:

(2-chloro-5-methyl-phenoxy)-acetic acid hydrazide (588680-02-8) → 3-(2-chloro-5-methylphenoxymethyl)-4-N-[pyrazin-2-carboxamido]-1,2,4-triazole-5-thiol

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / 2 h

2: 65 percent / 6 h / 160 - 180 °C / Heating

With potassium hydroxide; In ethanol;

DOI:10.1211/0022357011775307

upstream raw materials:

2-(2-chloro-5-methylphenoxy)acetic acid