1556-00-9

Basic information

• Product Name: (2-CHLORO-5-METHYL-PHENOXY)-ACETIC ACID
• Synonyms: (2-chloro-5-methylphenoxy)acetic acid(SALTDATA: FREE)
• CAS NO: 1556-00-9
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.62
• Mol File: 1556-00-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 148-149 °C
• Boiling Point: 334.3°Cat760mmHg
• Flash Point: 156°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 5.11E-05mmHg at 25°C
• Refractive Index: 1.552
• PKA: 3.08±0.10(Predicted)
• CAS DataBase Reference: (2-CHLORO-5-METHYL-PHENOXY)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-CHLORO-5-METHYL-PHENOXY)-ACETIC ACID(1556-00-9)
• EPA Substance Registry System: (2-CHLORO-5-METHYL-PHENOXY)-ACETIC ACID(1556-00-9)

Safety Data

• Hazardous Substances Data: 1556-00-9(Hazardous Substances Data)

Usage

Uses

(2-Chloro-5-methylphenoxy)acetic Acid is a reagent used in the synthesis of novel phenoxyacetoxy-thienyl-methylphosphinates which exhibit herbicidal and fungicidal activity.

InChI:InChI=1/C9H9ClO3/c1-6-2-3-7(10)8(4-6)13-5-9(11)12/h2-4H,5H2,1H3,(H,11,12)

Upstream product

• 615-74-7 2-chloro-5-methylphenol 
• 79-11-8 chloroacetic acid 
• 105-36-2 ethyl bromoacetate 
• 588679-09-8 C₁₁H₁₃ClO₃ 

Downstream Products

• 60222-55-1 2-(2-chloro-5-methyl-phenoxy)-ethanol 
• 588680-02-8 (2-chloro-5-methyl-phenoxy)-acetic acid hydrazide 
• 904702-56-3 O,O-dimethyl α-(5-methyl-2-chlorophenoxyacetoxy)-3-nitrobenzylphosphonate 
• 900502-08-1 C₁₇H₁₉ClNO₅P 

Relevant articles and documents

TRICYCLIC PIPERIDINE COMPOUNDS

The present invention relates to compounds of the formula (I), wherein R, R1a, R1b, R2, R3, and X are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), to methods for the preparation of such compounds of formula (I), and especially to their use as TPH modulators.

Studies of O,O-Dimethyl α-(2,4-Dichlorophenoxyacetoxy) ethylphosphonate (HW02) as a new herbicide. 1. Synthesis and herbicidal activity of HW02 and analogues as novel inhibitors of pyruvate dehydrogenase complex

On the basis of the previous work for optimization of O,O-diethyl α-(substituted phenoxyacetoxy)alkylphosphonates, further extensive syntheticmodifications were made to the substituents in alkylphosphonate and phenoxymoieties of the title compounds. New O,O-dimethyl α-(substituted phenoxyacetoxy)alkylphosphonates were synthesized as potential inhibitors of pyruvate dehydorogenase complex (PDHc). Their herbicidal activity and efficacy in vitro against PDHc were examined. Some of these compounds exhibited significant herbicidal activity and were demonstrated to be effective inhibitors of PDHc from three different plants. The structure-activity relationships of these compounds including previously reported analogous compoundswere studied by examining their herbicidal activities. Both inhibitory potency against PDHc and herbicidal activity of title compounds could be increased greatly by optimizing substituent groups of the title compounds. O,O-Dimethyl α-(2,4- dichlorophenoxyacetoxy)ethylphosphonate (I-5), which acted as a competitive inhibitor of PDHc with much higher inhibitory potency against PDHc from Pisum sativum and Phaseolus radiatus than from Oryza sativa, was found to be themost effective compound against broadleaf weeds and showed potential utility as herbicide.