N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin

Base Information

• Chemical Name: N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin
• CAS No.: 789462-13-1
• Molecular Formula: C₂₃H₂₇N
• Molecular Weight: 317.474
• Mol file: 789462-13-1.mol

Synonyms:

Chemical Property of N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin

There total 2 articles about N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-<4-(1,1-Dimethylethyl)phenylmethyl>-phthalimid (149879-57-2) → N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin (789462-13-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / hydrazine hydrate / ethanol / 12 h / 40 °C

2: 1) methanesulfonic acid, 2) NaBH₄ / 1) toluene, reflux, 3 h, 2) MeOH, 50 deg C, 2 h

With sodium tetrahydroborate; methanesulfonic acid; hydrazine hydrate; In ethanol;

DOI:10.1002/ardp.19933260607

Reference yield:

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene (18880-00-7) → N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin (789462-13-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / K₂CO₃ / dimethylformamide / 8 h / 190 °C

2: 96 percent / hydrazine hydrate / ethanol / 12 h / 40 °C

3: 1) methanesulfonic acid, 2) NaBH₄ / 1) toluene, reflux, 3 h, 2) MeOH, 50 deg C, 2 h

With sodium tetrahydroborate; methanesulfonic acid; potassium carbonate; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/ardp.19933260607

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin (789462-13-1) → N-<4-(1,1-Dimethylethyl)phenylmethyl>-α,N-dimethyl-1-naphthalinmethanamin-Hydrochlorid

Guidance literature:

With sodium tetrahydroborate; Yield given. Multistep reaction; 1) dioxane, reflux, 12 h, 2) MeOH, room temperature, 3 h;

DOI:10.1002/ardp.19933260607

upstream raw materials:

N-<4-(1,1-Dimethylethyl)phenylmethyl>-phthalimid

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

Refernces