beta-Aminoglutarylalanine

Base Information

Chemical Name:beta-Aminoglutarylalanine
CAS No.:124756-83-8
Molecular Formula:C₈H₁₄N₂O₅
Molecular Weight:218.21
Hs Code.:
DSSTox Substance ID:DTXSID90154480
Nikkaji Number:J3.292.705J
Wikidata:Q83021735
Mol file:124756-83-8.mol

Synonyms:beta-aminoglutarylalanine;D-beta-aminoglutaryl-Ala

Suppliers and Price of beta-Aminoglutarylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of beta-Aminoglutarylalanine

Chemical Property:

Vapor Pressure:1.91E-14mmHg at 25°C
Boiling Point:569.2°C at 760 mmHg
Flash Point:298.1°C
PSA：133.21000
Density:1.362g/cm³
LogP:0.30840
XLogP3:-4.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:218.09027155
Heavy Atom Count:15
Complexity:266

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)NC(=O)CC(CC(=O)O)N
Isomeric SMILES:C[C@@H](C(=O)O)NC(=O)C[C@@H](CC(=O)O)N

Technology Process of beta-Aminoglutarylalanine

There total 16 articles about beta-Aminoglutarylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 130737-75-6,130737-77-8
(3S)-3-benzyloxycarbonylaminoglutaryl-(S)-alanine

: 124756-83-8,124756-84-9
(3S)-3-aminoglutaryl-(S)-alanine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 2h;

Reference yield: 30.0%

: 130737-75-6,130737-77-8
(3R)-3-benzyloxycarbonylaminoglutaryl-(S)-alanine

: 124756-83-8,124756-84-9
(3R)-3-aminoglutaryl-(S)-alanine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃;

Reference yield:

: 1830-54-2
3-oxopentanedioic acid dimethyl ester

: 124756-83-8,124756-84-9
(3R)-3-aminoglutaryl-(S)-alanine

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) ammonium acetate, molecular sieves 3 Angstroem, 2.) methanolic HCl, NaBH₃CN / 1.) methanol, 2 d, 2.) pH 3, r.t., 1 h

2: 84 percent / aq. NaHCO₃ / toluene / 3 h / Ambient temperature

3: 82 percent / phosphate buffer, aq. NaOH / pig liver esterase / acetone / 7 h / 25 °C / pH 8

4: 83 percent / 4-dimethylaminopyridine, dicyclohexylcarbodiimide / CH₂Cl₂ / 1.) 0 deg C, 5 min, 2.) r.t., 3 h

5: 81 percent / aq. NaOH / methanol / 2.5 h / Ambient temperature

6: 67 percent / 2-isobutyloxy-1-isobutyloxycarbonyl-1,2-dihydroquinoline / tetrahydrofuran / 1.) r.t., 2.) reflux

7: 76 percent / CF₃COOH / CH₂Cl₂ / 1.5 h / Ambient temperature

8: 30 percent / H₂ / 10percent Pd-C / methanol / 20 °C

With ammonium acetate; hydrogenchloride; dmap; sodium hydroxide; phosphate buffer; 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline; 3 A molecular sieve; hydrogen; sodium cyanoborohydride; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; pig liver esterase; In tetrahydrofuran; methanol; dichloromethane; acetone; toluene;