C₁₄H₁₆BrNO₂S

Base Information

• Chemical Name: C₁₄H₁₆BrNO₂S
• CAS No.: 1374005-94-3
• Molecular Formula: C₁₄H₁₆BrNO₂S
• Molecular Weight: 342.257
• Mol file: 1374005-94-3.mol

Synonyms:

Chemical Property of C₁₄H₁₆BrNO₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₆BrNO₂S

There total 7 articles about C₁₄H₁₆BrNO₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-bromopent-4-en-1-yl)-4-methyl-N-((trimethylsilyl)ethynyl)benzenesulfonamide (1361583-16-5) → C14H16BrNO2S (1374005-94-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1002/chem.201102880

Reference yield:

N-(4-bromopent-4-en-1-yl)-4-methylbenzenesulfonamide → C14H16BrNO2S (1374005-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hexamethylsilazane / toluene / 0.5 h / -78 - 20 °C / Inert atmosphere

1.2: 18.17 h / -78 - 20 °C / Inert atmosphere

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; potassium hexamethylsilazane; In tetrahydrofuran; toluene;

DOI:10.1002/chem.201102880

Reference yield:

4-bromopent-4-en-1-ol (64180-78-5) → C14H16BrNO2S (1374005-94-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere

3.1: potassium hexamethylsilazane / toluene / 0.5 h / -78 - 20 °C / Inert atmosphere

3.2: 18.17 h / -78 - 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; potassium hexamethylsilazane; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; toluene; 1.1: Mitsunobu displacement;

DOI:10.1002/chem.201102880

upstream raw materials:

N-(4-bromopent-4-en-1-yl)-4-methyl-N-((trimethylsilyl)ethynyl)benzenesulfonamide

4-bromopent-4-en-1-ol

4-bromo-4-pentenoic acid tert-butyl ester

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide

Downstream raw materials:

N-(4-bromopent-4-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide

dimethyl 8-phenyl-1-tosyl-1,2,3,4,5,8-hexahydroquinoline-6,7-dicarboxylate

4-methyl-N-(pent-4-en-1-yl)-N-(phenylethynyl)benzenesulfonamide

(Z)-2-benzylidene-3-methylene-1-tosylpiperidine