N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide

Base Information

Chemical Name:N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide
CAS No.:120494-08-8
Molecular Formula:C₁₇H₁₅N₃O
Molecular Weight:277.326
Hs Code.:
DSSTox Substance ID:DTXSID601220736

Synonyms:N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide;DTXSID601220736;120494-08-8

Suppliers and Price of N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:277.121512110
Heavy Atom Count:21
Complexity:348

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=NC=C1)N2C=CC=C2)NC(=O)C3=CC=CC=C3

Technology Process of N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide

There total 3 articles about N-[4-Methyl-2-(1H-pyrrol-1-yl)-3-pyridinyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 98-88-4
benzoyl chloride

: 120494-06-6
amino-3 methyl-4 (pyrrolyl-1)-2 pyridine

: 120494-08-8
benzoylamino-3 methyl-4 (pyrrolyl-1)-2 pyridine

Guidance literature:: With triethylamine; In benzene; for 2h; Ambient temperature;
DOI:10.1248/cpb.36.3248

Reference yield:

: 6635-86-5,67476-70-4
2-amino-4-methyl-3-nitropyridine

: 120494-08-8
benzoylamino-3 methyl-4 (pyrrolyl-1)-2 pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / acetic acid / 2 h / Heating

2: 2.) hydrazine hydrate / 1.) Raney nickel / 1.) ethanol, 10 min. reflux; 2.) 4 h reflux

3: 68 percent / triethylamine / benzene / 2 h / Ambient temperature

With hydrazine hydrate; triethylamine; nickel; In acetic acid; benzene;
DOI:10.1248/cpb.36.3248

Reference yield:

: 120494-05-5
methyl-4 nitro-3 (pyrrolyl-1)-2 pyridine

: 120494-08-8
benzoylamino-3 methyl-4 (pyrrolyl-1)-2 pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) hydrazine hydrate / 1.) Raney nickel / 1.) ethanol, 10 min. reflux; 2.) 4 h reflux

2: 68 percent / triethylamine / benzene / 2 h / Ambient temperature

With hydrazine hydrate; triethylamine; nickel; In benzene;
DOI:10.1248/cpb.36.3248