C₂₀H₂₆N₄O₃

Base Information

• Chemical Name: C₂₀H₂₆N₄O₃
• CAS No.: 1318802-73-1
• Molecular Formula: C₂₀H₂₆N₄O₃
• Molecular Weight: 370.451
• Mol file: 1318802-73-1.mol

Synonyms:

Chemical Property of C₂₀H₂₆N₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₆N₄O₃

There total 11 articles about C₂₀H₂₆N₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H21NO4 (1318802-95-7) → C20H26N4O3 (1318802-73-1)

Guidance literature:

Multi-step reaction with 8 steps

1: N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydride / tetrahydrofuran

2: potassium tert-butylate / tert-butyl alcohol

3: potassium carbonate / N,N-dimethyl-formamide

4: dmap; triethylamine

5: water; sodium hydroxide

6: trifluoroacetic acid / dichloromethane

7: N-ethyl-N,N-diisopropylamine / butan-1-ol

8: boron tribromide / dichloromethane

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; potassium tert-butylate; water; boron tribromide; sodium hydride; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol; butan-1-ol; 1: Baker-Venkataraman transformation;

DOI:10.1016/j.bmcl.2011.05.081

Reference yield:

C17H21NO4 (1318803-02-9) → C20H26N4O3 (1318802-73-1)

Guidance literature:

Multi-step reaction with 7 steps

1: potassium tert-butylate / tert-butyl alcohol

2: potassium carbonate / N,N-dimethyl-formamide

3: dmap; triethylamine

4: water; sodium hydroxide

5: trifluoroacetic acid / dichloromethane

6: N-ethyl-N,N-diisopropylamine / butan-1-ol

7: boron tribromide / dichloromethane

With dmap; potassium tert-butylate; water; boron tribromide; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; In dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol; butan-1-ol;

DOI:10.1016/j.bmcl.2011.05.081

Reference yield:

C18H22N4O2 (1318803-09-6) → C20H26N4O3 (1318802-73-1)

Guidance literature:

Multi-step reaction with 6 steps

1: potassium carbonate / N,N-dimethyl-formamide

2: dmap; triethylamine

3: water; sodium hydroxide

4: trifluoroacetic acid / dichloromethane

5: N-ethyl-N,N-diisopropylamine / butan-1-ol

6: boron tribromide / dichloromethane

With dmap; water; boron tribromide; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; In dichloromethane; N,N-dimethyl-formamide; butan-1-ol;

DOI:10.1016/j.bmcl.2011.05.081

upstream raw materials:

C₁₇H₂₁NO₄

C₁₇H₂₁NO₄

C₁₈H₂₂N₄O₂

acetic acid-(3-acetyl-4-methoxy-anilide)