Technology Process of Phosphoric acid 4-allyl-1-benzyloxymethyl-4-methyl-2,5-dioxo-pyrrolidin-(3Z)-ylidenemethyl ester diethyl ester
There total 15 articles about Phosphoric acid 4-allyl-1-benzyloxymethyl-4-methyl-2,5-dioxo-pyrrolidin-(3Z)-ylidenemethyl ester diethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
3: 420 mg / ammonia / tetrahydrofuran; H2O / -75 °C
4: 80 percent / sodium ethoxyde / ethanol / 1.5 h / 20 °C
5: 250 mg / 0.3M hydrochloric acid / H2O / 3 h / Heating
6: 1.) di-isopropylethylamine / 1.) CH2Cl2, 0 deg C, 10 min, 2.) CH2Cl2, 18 deg C, 16 h
7: sodium hydride / tetrahydrofuran / 6 h / 18 °C
8: tetrahydrofuran / 0.75 h / 18 °C
With
hydrogenchloride; ammonia; sodium ethanolate; sodium hydride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; ethanol; water;
- Guidance literature:
-
Multi-step reaction with 7 steps
2: 420 mg / ammonia / tetrahydrofuran; H2O / -75 °C
3: 80 percent / sodium ethoxyde / ethanol / 1.5 h / 20 °C
4: 250 mg / 0.3M hydrochloric acid / H2O / 3 h / Heating
5: 1.) di-isopropylethylamine / 1.) CH2Cl2, 0 deg C, 10 min, 2.) CH2Cl2, 18 deg C, 16 h
6: sodium hydride / tetrahydrofuran / 6 h / 18 °C
7: tetrahydrofuran / 0.75 h / 18 °C
With
hydrogenchloride; ammonia; sodium ethanolate; sodium hydride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; ethanol; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) di-isopropylethylamine / 1.) CH2Cl2, 0 deg C, 10 min, 2.) CH2Cl2, 18 deg C, 16 h
2: sodium hydride / tetrahydrofuran / 6 h / 18 °C
3: tetrahydrofuran / 0.75 h / 18 °C
With
sodium hydride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran;
