(+/-)-18-Homooestron

Base Information

• Chemical Name: (+/-)-18-Homooestron
• CAS No.: 845-85-2
• Molecular Formula: C₁₉H₂₄O₂
• Molecular Weight: 284.398
• Mol file: 845-85-2.mol

Synonyms:

Chemical Property of (+/-)-18-Homooestron

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-18-Homooestron

There total 7 articles about (+/-)-18-Homooestron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

13-Ethyl-3-hydroxy-6,7,11,12,13,16-hexahydro-cyclopenta[a]phenanthren-17-one (845-89-6) → (+/-)-13β-Ethyl-3-hydroxy-8α-gona-1,3,5(10)-trien-17-on (845-85-2,845-86-3,845-87-4,2445-29-6,6544-68-9,20302-04-9,26788-32-9,34990-81-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00321a016

Reference yield:

(+/-)-13-ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one (848-07-7) → (+/-)-13β-Ethyl-3-hydroxy-8α-gona-1,3,5(10)-trien-17-on (845-85-2,845-86-3,845-87-4,2445-29-6,6544-68-9,20302-04-9,26788-32-9,34990-81-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd-C / methanol

2: Py*HCl / 190 °C

With hydrogen; pyridine hydrochloride; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00321a016

Reference yield:

(+/-)-13-ethyl-3-methoxygona-1,3,5(10),8-tetraen-17-one → (+/-)-13β-Ethyl-3-hydroxy-8α-gona-1,3,5(10)-trien-17-on (845-85-2,845-86-3,845-87-4,2445-29-6,6544-68-9,20302-04-9,26788-32-9,34990-81-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd-C / methanol; tetrahydrofuran

2: Py*HCl / 190 °C

With hydrogen; pyridine hydrochloride; palladium on activated charcoal; In tetrahydrofuran; methanol;

DOI:10.1021/jm00321a016

upstream raw materials:

13-Ethyl-3-hydroxy-6,7,11,12,13,16-hexahydro-cyclopenta[a]phenanthren-17-one

(+/-)-13-ethyl-3-methoxy-8α-gona-1,3,5(10)-trien-17-one

(+/-)-13-ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,8,14-pentaen-17-one

Downstream raw materials:

dl-3-Benzyloxy-13β-aethylgona-1,3,5(10)-trien-17-on

dl-3-Benzyloxy-13β-ethylgona-1,3,5(10)-trien-17β-ol

d-3-Benzyloxy-13β-ethylgona-1,3,5(10)-trien-17β-ol

l-3-Benzyloxy-13β-ethylgona-1,3,5(10)-trien-17β-ol