1,2,3,4-Tetrahydroquinolin-8-amine

Base Information

Chemical Name:1,2,3,4-Tetrahydroquinolin-8-amine
CAS No.:54012-92-9
Molecular Formula:C9H12 N2
Molecular Weight:148.208
Hs Code.:2933499090
DSSTox Substance ID:DTXSID9068900
Nikkaji Number:J429.234K
Wikidata:Q81995665
Mol file:54012-92-9.mol

Synonyms:54012-92-9;1,2,3,4-tetrahydroquinolin-8-amine;1,2,3,4-tetrahydro-quinolin-8-ylamine;8-AMINO-1,2,3,4-TETRAHYDROQUINOLINE;8-Quinolinamine, 1,2,3,4-tetrahydro-;1,2,3,4-Tetrahydro-8-quinolinamine;MFCD00047566;Oprea1_788305;SCHEMBL1082367;DTXSID9068900;1,2,3,4-tetrahydroquinoline-8-amine;AKOS000274381;1,2,3,4-Tetrahydro-8-quinolineamine;SB37578;8-amino- 1,2,3,4-tetrahydroquinoline;NS-01132;CS-0314714;FT-0731146;F83650

Suppliers and Price of 1,2,3,4-Tetrahydroquinolin-8-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1,2,3,4-Tetrahydro-8-quinolinamine 95
500mg
$ 539.00

J&W Pharmlab
1,2,3,4-Tetrahydro-quinolin-8-ylamine 97%
250mg
$ 275.00

Crysdot
1,2,3,4-Tetrahydroquinolin-8-amine 95+%
1g
$ 581.00

Chemenu
1,2,3,4-Tetrahydro-quinolin-8-ylamine 95%
1g
$ 549.00

American Custom Chemicals Corporation
8-AMINO-1,2,3,4-TETRAHYDROQUINOLINE 95.00%
5MG
$ 501.52

Alichem
1,2,3,4-Tetrahydroquinolin-8-amine
1g
$ 502.44

Total 11 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydroquinolin-8-amine

Chemical Property:

Vapor Pressure:0.000421mmHg at 25°C
Boiling Point:316°Cat760mmHg
PKA:6.51±0.20(Predicted)
Flash Point:169.3°C
PSA：38.05000
Density:1.101g/cm³
LogP:2.34610
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:148.100048391
Heavy Atom Count:11
Complexity:136

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-Tetrahydro-8-quinolinamine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C(=CC=C2)N)NC1

Technology Process of 1,2,3,4-Tetrahydroquinolin-8-amine

There total 4 articles about 1,2,3,4-Tetrahydroquinolin-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 8-{[(benzyloxy)carbonyl]amino}quinoline-1-oxide

: 578-66-5
8-amino quinoline

: 54012-92-9
8-amino-1,2,3,4-tetrahydroquinoline

Guidance literature:: With 5%-palladium/activated carbon; ammonium formate; In methanol; at 25 ℃; for 12h; under 760.051 Torr;
DOI:10.1002/chem.201503511

Reference yield:

: 91-22-5
quinoline

: 578-66-5
8-amino quinoline

: 54012-92-9
8-amino-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 3-chloro-benzenecarboperoxoic acid / chloroform / 4 h / Reflux

2: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver(I) triflimide; silver(I) acetate / methanol / 12 h / 50 °C / 760.05 Torr

3: ammonium formate; 5%-palladium/activated carbon / methanol / 12 h / 25 °C / 760.05 Torr

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; 5%-palladium/activated carbon; ammonium formate; silver(I) acetate; 3-chloro-benzenecarboperoxoic acid; silver(I) triflimide; In methanol; chloroform;
DOI:10.1002/chem.201503511

Reference yield:

: 1613-37-2
Quinoline N-oxide

: 578-66-5
8-amino quinoline

: 54012-92-9
8-amino-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver(I) triflimide; silver(I) acetate / methanol / 12 h / 50 °C / 760.05 Torr

2: ammonium formate; 5%-palladium/activated carbon / methanol / 12 h / 25 °C / 760.05 Torr

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; 5%-palladium/activated carbon; ammonium formate; silver(I) acetate; silver(I) triflimide; In methanol;
DOI:10.1002/chem.201503511