(+)-isonitramine

Base Information

• Chemical Name: (+)-isonitramine
• CAS No.: 120330-88-3
• Molecular Formula: C₁₀H₁₉NO
• Molecular Weight: 169.267
• Mol file: 120330-88-3.mol

Synonyms:

Chemical Property of (+)-isonitramine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-isonitramine

There total 86 articles about (+)-isonitramine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(6R,7R)-2-Benzyl-2-aza-spiro[5.5]undec-8-en-7-ol → (+/-)-isonitramine (49620-06-6,65620-67-9,82227-98-3,98392-13-3,120330-88-3)

Guidance literature:

With hydrogen; palladium dihydroxide;

DOI:10.1016/S0040-4039(00)99677-1

Reference yield: 96.0%

(6R,7R)-7-Hydroxy-2-aza-spiro[5.5]undecane-2-carboxylic acid benzyl ester → (+/-)-isonitramine (49620-06-6,65620-67-9,82227-98-3,98392-13-3,120330-88-3)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal;

DOI:10.1039/c39850000847

Reference yield: 95.0%

(+/-)-N-benzyl isonitramine (111423-98-4,112572-12-0,112572-13-1) → (+/-)-isonitramine (49620-06-6,65620-67-9,82227-98-3,98392-13-3,120330-88-3)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; for 3h; Heating;

upstream raw materials:

(+/-)-N-benzyl isonitramine

2-(toluene-4-sulfonyl)-2-aza-spiro[5.5]undecan-7-one

piperidin-2-one

3-(5-trimethylsilylpent-4-ynyl)piperidin-2-one

Downstream raw materials:

N-methyl-O-tosylisonitramine

(S)-8-[1-Phenyl-meth-(E)-ylidene]-2-aza-spiro[5.5]undecan-7-one