2-Benzamido-3-methoxy-3-phenylpropanoic acid

Base Information

• Chemical Name: 2-Benzamido-3-methoxy-3-phenylpropanoic acid
• CAS No.: 101878-17-5
• Molecular Formula: C₁₇H₁₇NO₄
• Molecular Weight: 299.326
• DSSTox Substance ID: DTXSID00392891
• Mol file: 101878-17-5.mol

Synonyms:2-benzamido-3-methoxy-3-phenylpropanoic acid;101878-17-5;DTXSID00392891

Chemical Property of 2-Benzamido-3-methoxy-3-phenylpropanoic acid

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 299.11575802
• Heavy Atom Count: 22
• Complexity: 373

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC(C1=CC=CC=C1)C(C(=O)O)NC(=O)C2=CC=CC=C2

Technology Process of 2-Benzamido-3-methoxy-3-phenylpropanoic acid

There total 5 articles about 2-Benzamido-3-methoxy-3-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2RS,3RS)-2-amino-3-methoxy-3-phenyl-propionic acid (52834-89-6,91176-69-1) → (2RS,3RS)-2-benzoylamino-3-methoxy-3-phenyl-propionic acid (101878-17-5)

Guidance literature:

DOI:10.1021/ja01272a027

Reference yield:

(2RS,3SR)-2-amino-3-methoxy-3-phenyl-propionic acid (52834-89-6,91176-69-1) → (2RS,3SR)-2-benzoylamino-3-methoxy-3-phenyl-propionic acid (101878-17-5)

Guidance literature:

DOI:10.1021/ja01272a027

Reference yield:

(2RS,3SR)-2-amino-3-methoxy-3-phenyl-propionic acid (52834-89-6,91176-69-1) + benzoyl chloride (98-88-4) → (2RS,3SR)-2-benzoylamino-3-methoxy-3-phenyl-propionic acid (101878-17-5)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jo01136a010 DOI:10.1246/bcsj.30.537

upstream raw materials:

(2RS,3SR)-2-amino-3-methoxy-3-phenyl-propionic acid

benzoyl chloride

(2RS,3RS)-2-amino-3-methoxy-3-phenyl-propionic acid

(4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one

Downstream raw materials:

4-(4-chloro-benzhydryl)-2-phenyl-4H-oxazol-5-one

4-(2-chloro-benzhydryl)-2-phenyl-4H-oxazol-5-one

4-(4-methyl-benzhydryl)-2-phenyl-4H-oxazol-5-one

4-(2-methyl-benzhydryl)-2-phenyl-4H-oxazol-5-one