N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester

Base Information

• Chemical Name: N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester
• CAS No.: 97652-45-4
• Molecular Formula: C₁₆H₂₁NO₅
• Molecular Weight: 307.346
• Mol file: 97652-45-4.mol

Synonyms:

Chemical Property of N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester

There total 2 articles about N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

methyl (2S)-2-amino-3-phenylpropanoate (2577-90-4) + O-Isopropyliden-D-glycerinsaeurechlorid (73945-73-0,90493-96-2,97673-82-0,116561-26-3) → N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester (97652-45-4)

Guidance literature:

In chloroform; for 18h;

DOI:10.1007/BF00799972

Reference yield:

Kaliumsalz der O-Isopropyliden-D-glycerinsaeure (14028-61-6,83400-91-3,117205-81-9,130111-05-6) → N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester (97652-45-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / SOCl₂, pyridine, DMF / diethyl ether / 2 h / Heating

2: 43 percent / CHCl₃ / 18 h

With pyridine; thionyl chloride; N,N-dimethyl-formamide; In diethyl ether; chloroform;

DOI:10.1007/BF00799972

Reference yield: 58.0%

N-(O-Isopropyliden-D-glyceroyl)-L-phenylalaninmethylester (97652-45-4) → N-(O-Isopropyliden-D-glyceroyl)-L-phenylalanin (97652-53-4)

Guidance literature:

With sodium hydroxide; In methanol; for 3h; Heating;

DOI:10.1007/BF00799972

upstream raw materials:

methyl (2S)-2-amino-3-phenylpropanoate

O-Isopropyliden-D-glycerinsaeurechlorid

Kaliumsalz der O-Isopropyliden-D-glycerinsaeure

Downstream raw materials:

N-(O-Isopropyliden-D-glyceroyl)-L-phenylalanin

N-D-glyceroyl-L-phenylalanin