(S)-N-Tosyl AMphetaMine

Base Information

• Chemical Name: (S)-N-Tosyl AMphetaMine
• CAS No.: 34542-12-6
• Molecular Formula: C₁₆H₁₉NO₂S
• Molecular Weight: 289.398
• Mol file: 34542-12-6.mol

Synonyms:

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of (S)-N-Tosyl AMphetaMine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Protected Amphetamine.

Technology Process of (S)-N-Tosyl AMphetaMine

There total 14 articles about (S)-N-Tosyl AMphetaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

amphetamine hydrochloride (2706-50-5,405-41-4) + p-toluenesulfonyl chloride (98-59-9) → 4-methyl-N-(1-phenylpropan-2-yl)benzenesulfonamide (6338-74-5,34542-12-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/anie.201600912

Reference yield: 88.0%

allylbenzene (300-57-2,57807-91-7) + toluene-4-sulfonamide (70-55-3) → 4-methyl-N-(1-phenylpropan-2-yl)benzenesulfonamide (6338-74-5,34542-12-6)

Guidance literature:

With silver hexafluoroantimonate; 1,2-bis-(diphenylphosphino)ethane; copper(ll) bromide; In 1,1,2,2-tetrachloroethane; at 100 ℃; for 48h; Inert atmosphere;

DOI:10.1002/adsc.201000536

Reference yield: 82.0%

phenylmagnesium bromide + 1-tosyl-2-methylaziridine (25856-77-3) → 4-methyl-N-(1-phenylpropan-2-yl)benzenesulfonamide (6338-74-5,34542-12-6)

Guidance literature:

In tetrahydrofuran; for 5h; Heating;

DOI:10.1002/prac.19933350105

upstream raw materials:

1-tosyl-2-methylaziridine

allylbenzene

toluene-4-sulfonamide

n-butyl(phenyl)tellane

Downstream raw materials:

Clobenzorex