(2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone

Base Information

• Chemical Name: (2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone
• CAS No.: 855614-21-0
• Molecular Formula: C₁₅H₁₆N₂O₃
• Molecular Weight: 272.304
• Mol file: 855614-21-0.mol

Synonyms:

Chemical Property of (2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone

There total 2 articles about (2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,6-diethoxy-pyrimidin-4-yl)-phenyl-methanol (857427-26-0) → (2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone (855614-21-0)

Guidance literature:

With pyridine; chromium(VI) oxide;

DOI:10.1021/ja01591a028

Reference yield:

2,4-diethoxy-6-bromo-pyrimidine (64188-82-5) → (2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone (855614-21-0)

Guidance literature:

Multi-step reaction with 2 steps

1: butyl lithium; diethyl ether / -80 °C / Behandeln des Reaktionsgemisches mit Benzaldehyd

2: CrO₃; pyridine

With pyridine; chromium(VI) oxide; n-butyllithium; diethyl ether;

DOI:10.1021/ja01591a028

Reference yield:

(2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone (855614-21-0) → 6-benzoyl uracil (15422-07-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01591a028

upstream raw materials:

(2,6-diethoxy-pyrimidin-4-yl)-phenyl-methanol

2,4-diethoxy-6-bromo-pyrimidine

Downstream raw materials:

6-benzoyl uracil