6-benzoylpyrimidine-2,4(1H,3H)-dione

Base Information

• Chemical Name: 6-benzoylpyrimidine-2,4(1H,3H)-dione
• CAS No.: 15422-07-8
• Molecular Formula: C₁₁H₈N₂O₃
• Molecular Weight: 216.196
• Mol file: 15422-07-8.mol

Synonyms:Uracil,6-benzoyl- (8CI); 6-Benzoyluracil; NSC 210518

Chemical Property of 6-benzoylpyrimidine-2,4(1H,3H)-dione

Chemical Property:

• Density: 1.352g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-benzoylpyrimidine-2,4(1H,3H)-dione

There total 4 articles about 6-benzoylpyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

→ 6-benzoyl uracil (15422-07-8)

Guidance literature:

With hydrogenchloride; In methanol; water; for 4h; Reflux;

Reference yield:

(2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone (855614-21-0) → 6-benzoyl uracil (15422-07-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01591a028

Reference yield:

(2,6-diethoxy-pyrimidin-4-yl)-phenyl-methanol (857427-26-0) → 6-benzoyl uracil (15422-07-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃; pyridine

2: aqueous HCl

With pyridine; chromium(VI) oxide; hydrogenchloride;

DOI:10.1021/ja01591a028

upstream raw materials:

(2,6-diethoxy-pyrimidin-4-yl)-phenyl ketone

(2,6-diethoxy-pyrimidin-4-yl)-phenyl-methanol

6-benzoyl-2,4-dimethoxypyrimidine

Refernces

• 1、 Bardagi, Javier I.,Rossi, Roberto A.. "A novel approach to the synthesis of 6-substituted uracils in three-step, one-pot reactions". . p. 4491 - 4495. Retrieved 2008/09/21.