(S)-1-phenylhexanol

Base Information

• Chemical Name: (S)-1-phenylhexanol
• CAS No.: 106623-83-0
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 106623-83-0.mol

Synonyms:

Chemical Property of (S)-1-phenylhexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-1-phenylhexanol

There total 57 articles about (S)-1-phenylhexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

caprophenone (942-92-7) → (R)-1-phenyl-1-hexanol (4471-05-0,65488-03-1,106623-83-0,138381-77-8)

Guidance literature:

caprophenone; With cobalt(II) acetate; bis-[2-((4S)-4-phenyl-4,5-dihydro-oxazol-2-yl)-phenyl]-amine; In tetrahydrofuran; at 65 ℃; Inert atmosphere;

With diethoxymethylane; In tetrahydrofuran; at 65 ℃; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/chem.200903118

Reference yield: 96.0%

caprophenone (942-92-7) → (S)-1-phenylhexanol (4471-05-0,65488-03-1,106623-83-0,138381-77-8)

Guidance literature:

With (mer-[(S,S)-1,5-dimethyl-2,4-bis(4-phenyl-1,3-oxazolin-2-yl)benzene^(1-)]Ru(CO)Cl)2(ZnCl₂); hydrogen; sodium methylate; (-)-(S)-1-Anthracen-9-ylethanol; In isopropyl alcohol; at 40 ℃; for 24h; under 22801.5 Torr; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Autoclave;

DOI:10.1039/c1cc16057e

Reference yield: 92.0%

dipentylzinc (14402-93-8) + benzaldehyde (100-52-7) → (S)-1-phenylhexanol (4471-05-0,65488-03-1,106623-83-0,138381-77-8)

Guidance literature:

With titanium(IV) isopropylate; bis((trimethylsilyl)methyl)zinc; N,N’-(1R,2R)-cyclohexane-1,2-diylbis(1,1,1-trifluoromethanesulfonamide); In diethyl ether; at -20 ℃;

DOI:10.1021/jo971488y

upstream raw materials:

1-Bromopentane

benzaldehyde

dipentylzinc

n-pentylmagnesium bromide