6-BroMo-8-Methyl-5-nitroquinoline

Base Information

• Chemical Name: 6-BroMo-8-Methyl-5-nitroquinoline
• CAS No.: 75908-52-0
• Molecular Formula: C₁₀H₇BrN₂O₂
• Molecular Weight: 267.082
• Mol file: 75908-52-0.mol

Synonyms:

Chemical Property of 6-BroMo-8-Methyl-5-nitroquinoline

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

6-Bromo-8-methyl-5-nitroquinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-BroMo-8-Methyl-5-nitroquinoline

There total 2 articles about 6-BroMo-8-Methyl-5-nitroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-bromo-8-methylquinoline (178396-31-1) → 6-bromo-8-methyl-5-nitro-quinoline (75908-52-0)

Guidance literature:

With sulfuric acid; nitric acid;

DOI:10.1021/ja01165a063

Reference yield:

acetic acid-(4-bromo-2-methyl-5-nitro-anilide) (90326-43-5) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 6-bromo-8-methyl-5-nitro-quinoline (75908-52-0)

Guidance literature:

With arsenic(V) oxide; sulfuric acid;

DOI:10.1021/ja01165a063

Reference yield:

6-bromo-8-methyl-5-nitro-quinoline (75908-52-0) → N-(6-bromo-8-methyl-[5]quinolyl)-benzamide

Guidance literature:

Multi-step reaction with 2 steps

1: Raney nickel; acetone / Hydrogenation

2: aqueous NaOH

With sodium hydroxide; nickel; acetone;

DOI:10.1021/ja01165a063

upstream raw materials:

6-bromo-8-methylquinoline

acetic acid-(4-bromo-2-methyl-5-nitro-anilide)

glycerol

Downstream raw materials:

6-bromo-8-methyl-[5]quinolylamine