4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy-
CAS No.:106445-82-3
Molecular Formula:C17H13ClO3
Molecular Weight:300.741
Hs Code.:
DSSTox Substance ID:DTXSID40419874
Wikidata:Q82231090

Synonyms:106445-82-3;3-(4-Chlorophenyl)-6-ethyl-7-hydroxy-4H-chromen-4-one;4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy-;Oprea1_425728;SCHEMBL12940987;DTXSID40419874;STL513181;AKOS001612389;EU-0003233;SR-01000417047;SR-01000417047-1

Suppliers and Price of 4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy-

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:300.0553220
Heavy Atom Count:21
Complexity:426

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)Cl

Technology Process of 4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy-

There total 4 articles about 4H-1-Benzopyran-4-one, 3-(4-chlorophenyl)-6-ethyl-7-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 96644-00-7
2-(4-Chloro-phenyl)-1-(5-ethyl-2,4-dihydroxy-phenyl)-ethanone

: 122-51-0
orthoformic acid triethyl ester

: 106445-82-3
3-(4-Chloro-phenyl)-6-ethyl-7-hydroxy-chromen-4-one

Guidance literature:: With piperidine; In pyridine; at 120 - 130 ℃; for 10h;
DOI:10.1007/BF00576209

Reference yield:

: 2896-60-8
4-ethyl-1,3-benzenediol

: 106445-82-3
3-(4-Chloro-phenyl)-6-ethyl-7-hydroxy-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / 1.) dry HCl, boron trifluoride etherate, 2.) water / 1.) halogen chloride passed 10h, 10h room temperature, 2.) 90 deg C, pH=1, 60 min

2: 91 percent / piperidine / pyridine / 10 h / 120 - 130 °C

With piperidine; hydrogenchloride; boron trifluoride diethyl etherate; water; In pyridine;
DOI:10.1007/BF00576209

Reference yield:

: 140-53-4
p-chlorobenzyl cyanide

: 106445-82-3
3-(4-Chloro-phenyl)-6-ethyl-7-hydroxy-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / 1.) dry HCl, boron trifluoride etherate, 2.) water / 1.) halogen chloride passed 10h, 10h room temperature, 2.) 90 deg C, pH=1, 60 min

2: 91 percent / piperidine / pyridine / 10 h / 120 - 130 °C

With piperidine; hydrogenchloride; boron trifluoride diethyl etherate; water; In pyridine;
DOI:10.1007/BF00576209