2H-1-Benzopyran-2-one, 3-(bromoacetyl)-6-chloro-

Base Information

• Chemical Name: 2H-1-Benzopyran-2-one, 3-(bromoacetyl)-6-chloro-
• CAS No.: 106577-99-5
• Molecular Formula: C11H6BrClO3
• Molecular Weight: 301.524
• DSSTox Substance ID: DTXSID50399294
• Nikkaji Number: J2.903.959C
• Wikidata: Q82201744
• Mol file: 106577-99-5.mol

Synonyms:106577-99-5;3-(2-bromoacetyl)-6-chlorochromen-2-one;2H-1-Benzopyran-2-one, 3-(bromoacetyl)-6-chloro-;3-(bromoacetyl)-6-chloro-2H-chromen-2-one;3-(2-bromoacetyl)-6-chloro-2H-chromen-2-one;DTXSID50399294;MFCD00768657;STL134836;AKOS005745020;FT-0760102;3-Bromoacetyl-6-chloro-2H-1-benzopyran-2-one;1-(6-Chloro-2-oxo-2H-1-benzopyran-3-yl)-2-bromoethanone

Chemical Property of 2H-1-Benzopyran-2-one, 3-(bromoacetyl)-6-chloro-

Chemical Property:

• PSA: 47.28000
• LogP: 3.02400
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 299.91888
• Heavy Atom Count: 16
• Complexity: 353

Purity/Quality:

3-(bromoacetyl)-6-chloro-2H-chromen-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1Cl)C=C(C(=O)O2)C(=O)CBr

Technology Process of 2H-1-Benzopyran-2-one, 3-(bromoacetyl)-6-chloro-

There total 3 articles about 2H-1-Benzopyran-2-one, 3-(bromoacetyl)-6-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-acetyl-6-chlorocoumarin (53653-66-0) → 3-(2-bromoacetyl)-6-chloro-2H-chromen-2-one (106577-99-5)

Guidance literature:

With copper(ll) bromide; In chloroform; ethyl acetate; Reflux;

DOI:10.1016/j.ejmech.2011.10.035

Reference yield:

4-chlorosalicylaldehyde (2420-26-0) → 3-(2-bromoacetyl)-6-chloro-2H-chromen-2-one (106577-99-5)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine / 0 - 5 °C

2: bromine / chloroform

With piperidine; bromine; In chloroform;

DOI:10.1016/j.ejmech.2012.11.046

Reference yield:

5-chlorosalicyclaldehyde (635-93-8) → 3-(2-bromoacetyl)-6-chloro-2H-chromen-2-one (106577-99-5)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine / ethanol / 20 °C

2: bromine / chloroform / 60 °C

With piperidine; bromine; In ethanol; chloroform;

DOI:10.1016/j.bmcl.2014.10.100

upstream raw materials:

3-acetyl-6-chlorocoumarin

4-chlorosalicylaldehyde

5-chlorosalicyclaldehyde

Downstream raw materials:

6-Chloro-3-(2-phenyl-thiazol-4-yl)-chromen-2-one

6-chloro-3-(2-(phenylsulfonyl)acetyl)-2H-chromen-2-one

6-chloro-3-[2-(4-methylphenylsulfonyl)acetyl]-2H-chromen-2-one

6-chloro-3-(2-(styrenesulfonyl)acetyl)-2H-2-chromen-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 106577-99-5 6-Chloro-3-(2-broMoacetyl)-2-chroMenone

Send

Send

Metric Ton KG G Pound L ML

Send

Send