Technology Process of 1-(6-Cyclohexyl-pyridin-2-yl)-ethanone
There total 4 articles about 1-(6-Cyclohexyl-pyridin-2-yl)-ethanone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C12H14N2; methylmagnesium bromide;
In
tetrahydrofuran; diethyl ether;
at -25 - 20 ℃;
Inert atmosphere;
With
hydrogenchloride; water;
In
tetrahydrofuran; diethyl ether;
at 0 - 20 ℃;
for 4.16667h;
Inert atmosphere;
DOI:10.1039/c9ob00770a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N,N-Dimethylcarbamoyl chloride / dichloromethane / 12 h / 25 °C / Inert atmosphere
2.1: tetrahydrofuran; diethyl ether / -25 - 20 °C / Inert atmosphere
2.2: 4.17 h / 0 - 20 °C / Inert atmosphere
With
N,N-Dimethylcarbamoyl chloride;
In
tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1039/c9ob00770a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 3-chloro-benzenecarboperoxoic acid / chloroform / 3.17 h / 0 - 20 °C / Inert atmosphere
2.1: N,N-Dimethylcarbamoyl chloride / dichloromethane / 12 h / 25 °C / Inert atmosphere
3.1: tetrahydrofuran; diethyl ether / -25 - 20 °C / Inert atmosphere
3.2: 4.17 h / 0 - 20 °C / Inert atmosphere
With
3-chloro-benzenecarboperoxoic acid; N,N-Dimethylcarbamoyl chloride;
In
tetrahydrofuran; diethyl ether; dichloromethane; chloroform;
DOI:10.1039/c9ob00770a
