2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester
CAS No.:114827-15-5
Molecular Formula:C₄₁H₄₉N₃O₁₁S
Molecular Weight:791.92
Hs Code.:

2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

Synonyms:

Suppliers and Price of 2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

There total 2 articles about 2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 114827-14-4
3'-O-mesyl-2',5'-di-O-pivaloylcytidine

: 114827-15-5
2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

Guidance literature:: With pyridine; for 3h; Ambient temperature;
DOI:10.1246/cl.1987.2419

Reference yield:

: 114827-12-2
N⁴,O^2',O^5'-tripivaloyl-3'-O-mesylcytidine

: 114827-15-5
2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / Mg(OMe)2 / benzene; methanol / 0.5 h / Ambient temperature

2: 96 percent / pyridine / 3 h / Ambient temperature

With pyridine; magnesium methanolate; In methanol; benzene;
DOI:10.1246/cl.1987.2419