1-(Oxolan-2-yl)propan-2-one

Base Information

• Chemical Name: 1-(Oxolan-2-yl)propan-2-one
• CAS No.: 1073-73-0
• Molecular Formula: C7H12O2
• DSSTox Substance ID: DTXSID10456054
• Nikkaji Number: J1.028.564J
• Mol file: 1073-73-0.mol

Synonyms:1-(oxolan-2-yl)propan-2-one;1073-73-0;2-Propanone, 1-(tetrahydro-2-furanyl)-;acetonyltetrahydrofuran;SCHEMBL1499962;2-(2-Oxopropyl)tetrahydrofuran;LHYVBWMBMGJLLI-UHFFFAOYSA-;DTXSID10456054;LHYVBWMBMGJLLI-UHFFFAOYSA-N;BAA07373;2-Propanone, 1-(2-tetrahydrofuryl);AKOS010015170;CS-0256509;EN300-64934;Z513734588;InChI=1/C7H12O2/c1-6(8)5-7-3-2-4-9-7/h7H,2-5H2,1H3

Chemical Property of 1-(Oxolan-2-yl)propan-2-one

Chemical Property:

• XLogP3: 0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 128.083729621
• Heavy Atom Count: 9
• Complexity: 110

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)CC1CCCO1

Technology Process of 1-(Oxolan-2-yl)propan-2-one

There total 11 articles about 1-(Oxolan-2-yl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C7H12O2 → 1-(tetrahydrofuran-2'-yl)propan-2-one (1073-73-0,161040-21-7)

Guidance literature:

With 9-amino(9-deoxy)epiquinidine di(trichloroacetic acid); dihydrogen peroxide; In 1,4-dioxane; at 32 ℃; for 36h;

DOI:10.1021/ja402058v

Reference yield: 79.0%

4-methoxy-hept-6-yn-1-ol (888938-10-1) → 1-(tetrahydrofuran-2'-yl)propan-2-one (1073-73-0,161040-21-7)

Guidance literature:

sodium tetrachloroaurate dihydrate; In dichloromethane; water; at 35 ℃; for 12h;

DOI:10.1021/ol060574u

Reference yield: 68.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + 2-methylpropenal (78-85-3,25120-30-3) → 1-(tetrahydrofuran-2'-yl)propan-2-one (1073-73-0,161040-21-7)

Guidance literature:

With N-hydroxyphthalimide; oxygen; cobalt(II) acetate; at 40 ℃; for 6h; under 760 Torr;

DOI:10.1016/S0040-4039(02)00613-5

upstream raw materials:

tetrahydrofuran

percarbonate de O,O-tert-butyle et O-isopropyle

2-methoxytetrahydrofuran

Isopropenyl acetate