Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate

Base Information

Chemical Name:Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate
CAS No.:171102-21-9
Molecular Formula:C₁₁H₁₀ClFO₃
Molecular Weight:244.65
Hs Code.:
European Community (EC) Number:891-356-3

Synonyms:Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate;171102-21-9;SCHEMBL6318986;QRRFIUQAXZIQMH-UHFFFAOYSA-N;MFCD16810306;AKOS012381130;CCOC(=O)CC(=O)C1=CC=C(Cl)C=C1F;CS-0308624;EN300-126032;Ethyl3-(4-chloro-2-fluorophenyl)-3-oxopropanoate;A1-10398;ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropionate

Suppliers and Price of Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:244.0302500
Heavy Atom Count:16
Complexity:270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C1=C(C=C(C=C1)Cl)F

Technology Process of Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate

There total 1 articles about Ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 446-30-0
4-chloro-2-fluorobenzoic acid

: 171102-21-9
ethyl 3-(4-chloro-2-fluorophenyl)-3-oxopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

2: 3 h / Reflux

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;