<(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle

Base Information

• Chemical Name: <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle
• CAS No.: 69998-62-5
• Molecular Formula: C₂₂H₂₂O₈
• Molecular Weight: 414.412
• Mol file: 69998-62-5.mol

Synonyms:

Chemical Property of <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle

There total 7 articles about <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2-bromo-3,4,5-tri-methoxybenzaldehyde (35274-53-4) + (iodo-2 methylenedioxy-4,5 benzyl)-3 butanolide-4 (69998-61-4) → <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle (69998-62-5)

Guidance literature:

With copper; at 230 ℃; for 0.25h;

DOI:10.1016/0040-4020(82)85093-X

Reference yield:

piperonal (120-57-0,30024-74-9) → <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle (69998-62-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 69.5 percent / Na / methanol / 1.33 h / Heating

2: 97.5 percent / H₂ / 5percent Pd/C / acetic acid / 16 h / 30 °C / 22800 Torr

3: 1.) KOH, 2.) Ca(BH₄)2 / 1.) H₂O, 2.) ethanol, 10 deg C, 2 h

4: 89 percent / I₂ / CF₃CO₂Ag / CHCl₃ / 3 h

5: 48 percent / Copper bronze / 0.25 h / 230 °C

With potassium hydroxide; calcium borohydride; hydrogen; iodine; sodium; copper; palladium on activated charcoal; silver trifluoroacetate; In methanol; chloroform; acetic acid;

DOI:10.1016/0040-4020(82)85093-X

Reference yield:

4-(1,3-benzodioxol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one (80483-34-7) → <(butanolidyl-4)-3 methyl>-2 formyl-6' methylenedioxy-4,5 trimethoxy-2',3',4' biphenyle (69998-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / I₂ / CF₃CO₂Ag / CHCl₃ / 3 h

2: 48 percent / Copper bronze / 0.25 h / 230 °C

With iodine; copper; silver trifluoroacetate; In chloroform;

DOI:10.1016/0040-4020(82)85093-X

upstream raw materials:

2-bromo-3,4,5-tri-methoxybenzaldehyde

(iodo-2 methylenedioxy-4,5 benzyl)-3 butanolide-4

piperonal

4-(1,3-benzodioxol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one

Downstream raw materials:

(+/-)-epipicrosteganol-8

(+/-)-8α-hydroxyisopicrostegane

(+/-)-picrostegane

(+/-)-isostegane