N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid

Base Information

• Chemical Name: N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid
• CAS No.: 86040-89-3
• Molecular Formula: C₄₉H₆₄N₄O₁₄P*Cl
• Molecular Weight: 999.492

Synonyms:

Chemical Property of N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid

There total 4 articles about N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucin-chlorid (86040-55-3) + N4-(2-Acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester (86040-79-1) → N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N4-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid (86040-89-3)

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In dichloromethane; 1) -10 deg C, 1 h, 2) 15 h, room temperature;

DOI:10.1002/jlac.198319830302

Reference yield:

L-isoleucine (73-32-5,959215-79-3,18875-42-8) → N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N4-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid (86040-89-3)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂

2: 78 percent / CHCl₃ / 8 h / -10 °C

3: 64 percent / (ethyl)-2-ethoxy-1,2-dihydro-1-quinolinecarboxylate / CH₂Cl₂ / 1) -10 deg C, 1 h, 2) 15 h, room temperature

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine; In dichloromethane; chloroform;

DOI:10.1002/jlac.198319830302

Reference yield:

N4-(2-Acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-N2-<2-(triphenylphosphonio)ethoxycarbonyl>asparagin-tert-butylester-chlorid (86088-20-2) → N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N4-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid (86040-89-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / morpholine / CH₂Cl₂ / 0.33 h / Ambient temperature

2: 64 percent / (ethyl)-2-ethoxy-1,2-dihydro-1-quinolinecarboxylate / CH₂Cl₂ / 1) -10 deg C, 1 h, 2) 15 h, room temperature

With morpholine; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In dichloromethane;

DOI:10.1002/jlac.198319830302

upstream raw materials:

N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucin-chlorid

N⁴-(2-Acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester

L-isoleucine

N⁴-(2-Acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-N²-<2-(triphenylphosphonio)ethoxycarbonyl>asparagin-tert-butylester-chlorid

Downstream raw materials:

N-<2-(Triphenylphosphonio)ethoxycarbonyl>prolyl-isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 86040-89-3 N-<2-(Triphenylphosphonio)ethoxycarbonyl>isoleucyl-N⁴-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-asparagin-tert-butylester-chlorid

Send

Send

Metric Ton KG G Pound L ML

Send

Send