JWH 073 N-butanoic acid metabolite

Base Information

Chemical Name:JWH 073 N-butanoic acid metabolite
CAS No.:1307803-52-6
Molecular Formula:C₂₃H₁₉NO₃
Molecular Weight:357.409
Hs Code.:
DSSTox Substance ID:DTXSID401016341
Nikkaji Number:J2.980.373K
ChEMBL ID:CHEMBL4456796

Synonyms:JWH 073 N-butanoic acid metabolite;1307803-52-6;JWH-073 Butanoic Acid;4-[3-(naphthalene-1-carbonyl)indol-1-yl]butanoic acid;CHEMBL4456796;4-(3-(1-Naphthoyl)-1H-indol-1-yl)butanoic acid;SCHEMBL15112091;CHEBI:188295;DTXSID401016341;BDBM50534495;4-[3-(1-Naphthylcarbonyl)-1H-indole-1-yl]butyric acid

Suppliers and Price of JWH 073 N-butanoic acid metabolite

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
JWH-073 4-Butanoic acid metabolite solution
036-1ml
$ 214.00

Medical Isotopes, Inc.
JWH-073ButanoicAcid(100ug/mLinMethanol)
10 ml
$ 2200.00

Medical Isotopes, Inc.
JWH-073ButanoicAcid(100ug/mLinMethanol)
1 ml
$ 650.00

Cayman Chemical
JWH 073 N-butanoic acid metabolite ≥98%
10mg
$ 350.00

Cayman Chemical
JWH 073 N-butanoic acid metabolite ≥98%
5mg
$ 225.00

Cayman Chemical
JWH 073 N-butanoic acid metabolite ≥98%
1mg
$ 95.00

AK Scientific
4-(3-(1-Naphthoyl)-1H-indol-1-yl)butanoicacid
5mg
$ 403.00

Total 9 raw suppliers

Chemical Property of JWH 073 N-butanoic acid metabolite

Chemical Property:

Flash Point:9°C
Storage Temp.:-20°C
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:357.13649347
Heavy Atom Count:27
Complexity:548

Purity/Quality:

99% ^*data from raw suppliers

JWH-073 4-Butanoic acid metabolite solution ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2C(=O)C3=CN(C4=CC=CC=C43)CCCC(=O)O
Description JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-butanoic acid metabolite is expected to be a urinary metabolite of JWH 073, characterized by carboxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018. In urine samples, this metabolite of JWH 018 is almost completely glucuronidated.

Technology Process of JWH 073 N-butanoic acid metabolite

There total 1 articles about JWH 073 N-butanoic acid metabolite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1541244-60-3
ethyl 4-[3-(naphthalene-1-carbonyl)-1H-indol-1-yl]butanoate

: 1307803-52-6
4-[3-(naphthalene-1-carbonyl)-1H-indol-1-yl]butanoic acid

Guidance literature:: With water; sodium hydroxide; In methanol; at 50 ℃; for 2h;
DOI:10.1021/acs.jmedchem.6b00516

Reference yield:

: 1307803-52-6
4-[3-(naphthalene-1-carbonyl)-1H-indol-1-yl]butanoic acid

: 2616-64-0
UDP-glucuronic acid

: 1322008-40-1
C₂₉H₂₇NO₉

Guidance literature:: With human liver microsomes; In dimethyl sulfoxide; at 37 ℃; for 1.5h; pH=7.4; Reagent/catalyst; Kinetics; aq. buffer; Microbiological reaction;
DOI:10.1124/dmd.111.040709