N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide

Base Information

Chemical Name:N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide
CAS No.:108009-19-4
Molecular Formula:C15H11BrN2O5
Molecular Weight:379.167
Hs Code.:
DSSTox Substance ID:DTXSID40549988
Wikidata:Q82429194

Synonyms:108009-19-4;N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide;DTXSID40549988

Suppliers and Price of N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:377.98513
Heavy Atom Count:23
Complexity:451

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)ON(C1=CC=C(C=C1)Br)C(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide

There total 6 articles about N-(Acetyloxy)-N-(4-bromophenyl)-4-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 3623-23-2
4-bromonitrosobenzene

: 122-04-3
4-nitro-benzoyl chloride

: 2-(α-hydroxyethyl)-3,4-dimethylthiazolium trifluoromethanesulfonate

: 108009-19-4
O-acetyl-N-(4-nitrobenzoyl)-N-(4-bromophenyl)hydroxylamine

: 1215-42-5,21650-67-9,125367-64-8
1,2-bis(4-bromophenyl)diazene oxide

Guidance literature:: 4-bromonitrosobenzene; 2-(α-hydroxyethyl)-3,4-dimethylthiazolium trifluoromethanesulfonate; In dichloromethane; at 20 ℃;

4-nitro-benzoyl chloride; With sodium hydride; In tetrahydrofuran; at -30 - 20 ℃; Further stages.;
DOI:10.1016/j.tet.2008.06.008

Reference yield: 28.0%

: 10468-46-9
N-(4-bromophenyl)hydroxylamine

: 122-04-3
4-nitro-benzoyl chloride

: 136696-42-9
2-acetyl-3,4-dimethylthiazolium triflate

: 59280-03-4
N-(4'-bromophenyl)-4-nitrobenzamide

: 108009-19-4
O-acetyl-N-(4-nitrobenzoyl)-N-(4-bromophenyl)hydroxylamine

: 1215-42-5,21650-67-9,125367-64-8
1,2-bis(4-bromophenyl)diazene oxide

Guidance literature:: With sodium hydride; triethylamine; Product distribution; multistep reaction;
DOI:10.1016/S0040-4020(98)01161-2

Reference yield:

: 10468-46-9
N-(4-bromophenyl)hydroxylamine

: 108009-19-4
O-acetyl-N-(4-nitrobenzoyl)-N-(4-bromophenyl)hydroxylamine

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / Ambient temperature

2: Et₃N / tetrahydrofuran / -50 - -40 °C

With triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)79231-8