Boron, [1-cyclopropyl-7-[4-[(1,1-diMethylethoxy)carbonyl]-2-Methyl-1-piperazinyl]-6-fluoro-1,4-dihydro-8-Methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3]difluoro-, (T-4)-

Base Information

Chemical Name:Boron, [1-cyclopropyl-7-[4-[(1,1-diMethylethoxy)carbonyl]-2-Methyl-1-piperazinyl]-6-fluoro-1,4-dihydro-8-Methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3]difluoro-, (T-4)-
CAS No.:1219495-03-0
Molecular Formula:C₂₄H₂₉BF₃N₃O₆
Molecular Weight:523.317
Hs Code.:

Boron, [1-cyclopropyl-7-[4-[(1,1-diMethylethoxy)carbonyl]-2-Methyl-1-piperazinyl]-6-fluoro-1,4-dihydro-8-Methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3]difluoro-, (T-4)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Boron, [1-cyclopropyl-7-[4-[(1,1-diMethylethoxy)carbonyl]-2-Methyl-1-piperazinyl]-6-fluoro-1,4-dihydro-8-Methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3]difluoro-, (T-4)-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of Boron, [1-cyclopropyl-7-[4-[(1,1-diMethylethoxy)carbonyl]-2-Methyl-1-piperazinyl]-6-fluoro-1,4-dihydro-8-Methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3]difluoro-, (T-4)-

There total 4 articles about Boron, [1-cyclopropyl-7-[4-[(1,1-diMethylethoxy)carbonyl]-2-Methyl-1-piperazinyl]-6-fluoro-1,4-dihydro-8-Methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3]difluoro-, (T-4)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112811-71-9
ethyl 8-methoxy-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

: 1219495-03-0
C₂₄H₂₉BF₃N₃O₆

Guidance literature:: Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / tetrahydrofuran / 48 h / Reflux; Inert atmosphere

2: dimethyl sulfoxide / 72 h / 0 - 40 °C / Inert atmosphere

With boron trifluoride diethyl etherate; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.14233/ajchem.2014.15572

Reference yield:

: (1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-(oxo-κO)-3-quinoline-carboxylato-κO3)difluoro-Boron

: 120737-59-9
3-methyl-piperazine-1-carboxylic acid tert-butyl ester

: 1219495-03-0
C₂₄H₂₉BF₃N₃O₆

Guidance literature:: In dimethyl sulfoxide; at 0 - 40 ℃; for 72h; Inert atmosphere;
DOI:10.14233/ajchem.2014.15572

Reference yield:

: 55130-19-3
di-tert-butyl dicarbonate

: 1219495-03-0
C₂₄H₂₉BF₃N₃O₆

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 1 h / 0 °C / Inert atmosphere

2: dimethyl sulfoxide / 72 h / 0 - 40 °C / Inert atmosphere

In dichloromethane; dimethyl sulfoxide;
DOI:10.14233/ajchem.2014.15572