N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide)

Base Information

• Chemical Name: N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide)
• CAS No.: 1400565-40-3
• Molecular Formula: C₅₁H₅₄F₉N₉O₁₂
• Molecular Weight: 1156.03
• Mol file: 1400565-40-3.mol

Synonyms:

Chemical Property of N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide)

There total 10 articles about N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)triethanaminium tris(2,2,2-trifluoroacetate) + 1-<<4-<3-(trifluoromethyl)-3H-diazirin-3-yl>benzoyl>oxy>-2,5-pyrrolidinedione (87736-89-8) → N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide) (1400565-40-3)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1055/s-0031-1290444

Reference yield:

2,2,2-trifluoro-1-(p-tolyl)ethanone (394-59-2) → N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide) (1400565-40-3)

Guidance literature:

Multi-step reaction with 7 steps

1: pyridine; hydroxylamine hydrochloride / ethanol / 80 °C

2: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 0 - 20 °C

3: ammonia / diethyl ether / -78 °C

4: pyridine; pyridinium chlorochromate / dichloromethane / 0 °C

5: potassium permanganate / pyridine; water / 50 °C

6: dicyclohexyl-carbodiimide / dichloromethane / 2 h / 20 °C

7: triethylamine / dichloromethane

With pyridine; dmap; potassium permanganate; hydroxylamine hydrochloride; ammonia; triethylamine; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; pyridinium chlorochromate; In pyridine; diethyl ether; ethanol; dichloromethane; water;

DOI:10.1055/s-0031-1290444

Reference yield:

3,5-dihydroxyphenol (108-73-6) → N,N',N''-(2,2',2''-(2,2',2''-(2,2',2''-(benzene-1,3,5-triyltris(oxy))tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(oxy)tris(ethane-2,1-diyl))tris(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide) (1400565-40-3)

Guidance literature:

Multi-step reaction with 3 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran

2: dichloromethane / 1 h / 20 °C

3: triethylamine / dichloromethane

With triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; 1: Mitsunobu reaction;

DOI:10.1055/s-0031-1290444

upstream raw materials:

3,5-dihydroxyphenol

1-<<4-<3-(trifluoromethyl)-3H-diazirin-3-yl>benzoyl>oxy>-2,5-pyrrolidinedione

C₃₉H₆₉N₃O₁₅

2,2,2-trifluoro-1-(p-tolyl)ethanone