6-Bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

Base Information

Chemical Name:6-Bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde
CAS No.:36225-16-8
Molecular Formula:C8H6 Br N O5
Molecular Weight:276.043
Hs Code.:
NSC Number:95681
DSSTox Substance ID:DTXSID40294269
Wikidata:Q82033478

Synonyms:6-bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde;36225-16-8;NSC95681;NCIOpen2_005912;DTXSID40294269;NSC-95681;A823252;6-bromanyl-3-methoxy-2-nitro-4-oxidanyl-benzaldehyde

Suppliers and Price of 6-Bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 6-Bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

Chemical Property:

Vapor Pressure:2.44E-07mmHg at 25°C
Boiling Point:410.9°C at 760 mmHg
Flash Point:202.3°C
Density:1.821g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:274.94293
Heavy Atom Count:15
Complexity:256

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1O)Br)C=O)[N+](=O)[O-]

Technology Process of 6-Bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

There total 5 articles about 6-Bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 90766-55-5
4-acetoxy-6-bromo-3-methoxy-2-nitrobenzaldehyde

: 36225-16-8
6-bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

Guidance literature:: With water; sodium hydroxide; at 40 ℃; for 1h; Inert atmosphere;
DOI:10.1055/s-0039-1690164

Reference yield:

: 36225-16-8
6-bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

Guidance literature:: With nitric acid; at 0 - 6 ℃; Nitrierung und nachfolgenden Verseifung;

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 36225-16-8
6-bromo-4-hydroxy-3-methoxy-2-nitrobenzaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: dmap / 2 h / 40 °C

2: bromine; potassium bromide / acetonitrile; water / 20 h / 20 °C

3: nitric acid / water / 0.17 h / 0 - 6 °C

4: sodium hydroxide; water / 1 h / 40 °C / Inert atmosphere

With dmap; water; bromine; nitric acid; potassium bromide; sodium hydroxide; In water; acetonitrile;
DOI:10.1055/s-0039-1690164