BOC-NVA-OSU

Base Information

Chemical Name:BOC-NVA-OSU
CAS No.:108233-37-0
Molecular Formula:C₁₄H₂₂N₂O₆
Molecular Weight:314.338
Hs Code.:
Mol file:108233-37-0.mol

Synonyms:t-BOC-Leu-OSu;(S)-2-tert-Butoxycarbonylamino-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester;Boc-Nva-ONSu;Boc-Nva-OSu;

Suppliers and Price of BOC-NVA-OSU

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Boc-L-norvaline N-hydroxysuccinimide ester
500mg
$ 333.00

Crysdot
Boc-Nva-Osu 95+%
5g
$ 470.00

Chemenu
Boc-Nva-Osu 95%
5g
$ 444.00

American Custom Chemicals Corporation
BOC-NVA-OSU 95.00%
1G
$ 455.00

American Custom Chemicals Corporation
BOC-NVA-OSU 95.00%
5MG
$ 400.27

AK Scientific
Boc-Nva-Osu
1g
$ 104.00

Total 13 raw suppliers

Chemical Property of BOC-NVA-OSU

Chemical Property:

PSA：102.01000
LogP:1.61580

Purity/Quality:

97% ^*data from raw suppliers

Boc-L-norvaline N-hydroxysuccinimide ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of BOC-NVA-OSU

There total 3 articles about BOC-NVA-OSU which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 53308-95-5
N-tert-butoxycarbonyl-L-norvaline

: 108233-37-0
N-t-BOC-L-Nor-N-hydroxysuccinimide

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at -5 - 20 ℃; for 3h;
DOI:10.1006/bioo.1996.0034

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 108233-37-0
N-t-BOC-L-Nor-N-hydroxysuccinimide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 0.17 h / 0 °C

1.2: 24 h / 0 - 20 °C

2.1: dicyclohexyl-carbodiimide / dichloromethane / 2 h / 10 - 20 °C / Inert atmosphere

With dicyclohexyl-carbodiimide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/anie.201507321

Reference yield:

: 6600-40-4,498-18-0
L-Norvaline

: 108233-37-0
N-t-BOC-L-Nor-N-hydroxysuccinimide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 0.17 h / 0 °C

1.2: 24 h / 0 - 20 °C

2.1: dicyclohexyl-carbodiimide / dichloromethane / 2 h / 10 - 20 °C / Inert atmosphere

With dicyclohexyl-carbodiimide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/anie.201507321