Technology Process of 5-Decyl-2-(1,4,7,10,13,16-hexaoxa-cyclononadec-8-ylmethoxy)-benzoic acid
There total 13 articles about 5-Decyl-2-(1,4,7,10,13,16-hexaoxa-cyclononadec-8-ylmethoxy)-benzoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium hydroxide;
for 4h;
Heating;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) potassium t-butoxide / 1.) THF, room temperature, 1 h; 2.) room temperature, 2 d, then reflux, 24 h
2: H2, p-toluenesulfonic acid / 10percent Pd on carbon / ethanol / 24 h / 760 Torr
3: 91 percent / pyridine / 4 °C / overnight
4: 1.) NaH / 1.) THF, room temperature, 1 h; 2.) reflux, 72 h
5: 94 percent / 1.) 15percent aq. NaOH; 2.) 6 N HCl / 4 h / Heating
With
hydrogenchloride; sodium hydroxide; potassium tert-butylate; hydrogen; sodium hydride; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
pyridine; ethanol;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: H2, p-toluenesulfonic acid / 10percent Pd on carbon / ethanol / 24 h / 760 Torr
2: 91 percent / pyridine / 4 °C / overnight
3: 1.) NaH / 1.) THF, room temperature, 1 h; 2.) reflux, 72 h
4: 94 percent / 1.) 15percent aq. NaOH; 2.) 6 N HCl / 4 h / Heating
With
hydrogenchloride; sodium hydroxide; hydrogen; sodium hydride; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
pyridine; ethanol;
