Technology Process of C18H22N2O3
There total 4 articles about C18H22N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanesulfonic acid;
In
1,4-dioxane;
at 120 ℃;
for 17h;
Inert atmosphere;
DOI:10.1021/jm501863r
- Guidance literature:
-
Multi-step reaction with 4 steps
1: nitric acid; zinc(II) chloride / ethyl acetate / 0.8 h / Sonication; Cooling with ice
2: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / 70 °C / Inert atmosphere
3: hydrogen; palladium 10% on activated carbon / methanol / 5.5 h / 20 °C
4: methanesulfonic acid / 1,4-dioxane / 17 h / 120 °C / Inert atmosphere
With
methanesulfonic acid; palladium 10% on activated carbon; hydrogen; nitric acid; potassium carbonate; potassium iodide; zinc(II) chloride;
In
1,4-dioxane; methanol; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm501863r
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / 70 °C / Inert atmosphere
2: hydrogen; palladium 10% on activated carbon / methanol / 5.5 h / 20 °C
3: methanesulfonic acid / 1,4-dioxane / 17 h / 120 °C / Inert atmosphere
With
methanesulfonic acid; palladium 10% on activated carbon; hydrogen; potassium carbonate; potassium iodide;
In
1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm501863r
