3-iodo-2-methoxyphenylboronic acid

Base Information

• Chemical Name: 3-iodo-2-methoxyphenylboronic acid
• CAS No.: 1257793-14-8
• Molecular Formula: C₇H₈BIO₃
• Molecular Weight: 277.854
• Mol file: 1257793-14-8.mol

Synonyms:

Chemical Property of 3-iodo-2-methoxyphenylboronic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-iodo-2-methoxyphenylboronic acid

There total 2 articles about 3-iodo-2-methoxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-methoxy-3-(trimethylsilyl)phenylboronic acid (1257792-97-4) + Iodine monochloride (7790-99-0) → 3-iodo-2-methoxyphenylboronic acid (1257793-14-8)

Guidance literature:

In chloroform; (Ar); stirring stoich. mixt. of boronic acid deriv. and ICl in CHCl3 at 0°C for 12 h; concg., addn. of diethyl ether, addn. of aq. Na2S2O3, separating organicphase, evapn., filtration, washing with CHCl3, elem. anal.;

DOI:10.1016/j.jorganchem.2010.08.016

Reference yield:

2-methoxy-3-(trimethylsilyl)phenylboronic acid (1257792-97-4) + Iodine monochloride (7790-99-0) → 3-iodo-2-methoxyphenylboronic acid (1257793-14-8) + 3,5-diiodo-2-methoxyphenylboronic acid (1072951-59-7)

Guidance literature:

In chloroform; (Ar); refluxing boronic acid deriv. and excess of ICl in CHCl3 for 6 h;

DOI:10.1016/j.jorganchem.2010.08.016

upstream raw materials:

2-methoxy-3-(trimethylsilyl)phenylboronic acid

Iodine monochloride

Refernces