7-(4-methoxybenzyl)-3-(4-methylphenyl)-9-[(4-methylphenylyl)-2H-1,2,3-triazol-2-yl]-1-oxa-4,7-diazaspiro[4.4]non-3-en-8-one

Base Information

• Chemical Name: 7-(4-methoxybenzyl)-3-(4-methylphenyl)-9-[(4-methylphenylyl)-2H-1,2,3-triazol-2-yl]-1-oxa-4,7-diazaspiro[4.4]non-3-en-8-one
• CAS No.: 1449507-89-4
• Molecular Formula: C₃₀H₂₉N₅O₃
• Molecular Weight: 507.592
• Mol file: 1449507-89-4.mol

Synonyms:

Chemical Property of 7-(4-methoxybenzyl)-3-(4-methylphenyl)-9-[(4-methylphenylyl)-2H-1,2,3-triazol-2-yl]-1-oxa-4,7-diazaspiro[4.4]non-3-en-8-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(4-methoxybenzyl)-3-(4-methylphenyl)-9-[(4-methylphenylyl)-2H-1,2,3-triazol-2-yl]-1-oxa-4,7-diazaspiro[4.4]non-3-en-8-one

There total 1 articles about 7-(4-methoxybenzyl)-3-(4-methylphenyl)-9-[(4-methylphenylyl)-2H-1,2,3-triazol-2-yl]-1-oxa-4,7-diazaspiro[4.4]non-3-en-8-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

3-p-tolyl-2H-azirine (32687-33-5) + 3-Diazo-1-(4-methoxy-benzyl)-pyrrolidine-2,4-dione (170707-44-5) → (3aRS,6aRS)-6a-hydroxy-5-(4-methoxybenzyl)-2-(4-methylphenyl)-3a-[4-(4-methylphenyl)-2H-1,2,3-triazol-2-yl]-3a,5,6,6a-tetrahydropyrrolo[3,4-b]pyrrol-4(3H)-one + 7-(4-methoxybenzyl)-3-(4-methylphenyl)-9-[(4-methylphenylyl)-2H-1,2,3-triazol-2-yl]-1-oxa-4,7-diazaspiro[4.4]non-3-en-8-one (1449507-89-4)

Guidance literature:

With copper acetylacetonate; In dichloromethane; at 100 ℃; for 10h; Concentration; Overall yield = 7%; Overall yield = 15 mg; Sealed tube;

DOI:10.1039/c3ob40708j

upstream raw materials:

3-p-tolyl-2H-azirine

3-Diazo-1-(4-methoxy-benzyl)-pyrrolidine-2,4-dione