170707-44-5Relevant academic research and scientific papers
Design and implementation of an efficient synthetic approach to furanosylated indolocarbazoles: Total synthesis of (+)- and (-)-K252a
Wood, John L.,Stoltz, Brian M.,Dietrich, Hans-Jürgen,Pflum, Derek A.,Petsch, Dejah T.
, p. 9641 - 9651 (2007/10/03)
The first total synthesis of the natural product (+)-K252a (2) has been achieved in 12 steps from commercially available materials, with a longest linear sequence of seven steps and an overall yield of 21%. The synthetic strategy employs novel rhodium carbenoid chemistry in the construction of both the indolocarbazole aglycon (4) and the carbohydrate moiety (9).
