Technology Process of 5-[(E)-(4-Chlorophenyl)diazenyl]pyrimidine-2,4,6(1H,3H,5H)-trione
There total 1 articles about 5-[(E)-(4-Chlorophenyl)diazenyl]pyrimidine-2,4,6(1H,3H,5H)-trione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-chloro-aniline;
With
nitrosylsulfuric acid; sulfuric acid;
In
water;
at 10 ℃;
for 0.833333h;
BARBITURIC ACID;
With
potassium hydroxide;
In
water;
at 27 - 80 ℃;
for 3h;
pH=4 - 6;
- Guidance literature:
-
In
1,4-dioxane; ethanol;
subst. barbituric acid dissolved in 1,4-dioxane by heating, soln. FeCl3 in alcohol added, refluxed (1h), pptn. on cooling; filtered, washed (hot water), dried (vac., P4O10), elem. anal.;
- Guidance literature:
-
In
1,4-dioxane; ethanol; ammonia;
aq. ammonia=NH3; metal acetate in 25% ammonia soln. and EtOH refluxed (1 h) with subst. barbituric acid dissolved in 1,4-dioxane; mixt. left overnight (pptn.), filtered, washed (hot water), dried (vac., P4O10), elem. anal.;
