(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid

Base Information

• Chemical Name: (S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid
• CAS No.: 141824-04-6
• Molecular Formula: C₃₀H₄₀N₆O₉S₂
• Molecular Weight: 692.814
• Mol file: 141824-04-6.mol

Synonyms:

Chemical Property of (S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid

There total 1 articles about (S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

BOC-glycine (4530-20-5) + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + (2S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-3-nitro-phenyl)-propionic acid (5575-03-1) + Nα-Boc-(S-p-MeBzl)-D-penicillamine (115962-34-0) → (S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid (141824-04-6)

Guidance literature:

Multistep reaction;

DOI:10.1021/jm00091a006

Reference yield:

(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-3-mercapto-3-methyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-3-mercapto-3-methyl-butyric acid (141824-04-6) → <3'-NO2Tyr1>DPDPE (129048-75-5)

Guidance literature:

With ammonium hydroxide; potassium hexacyanoferrate(III); In water; N,N-dimethyl-formamide; Yield given;

DOI:10.1021/jm00091a006

upstream raw materials:

BOC-glycine

N-tert-butoxycarbonyl-L-phenylalanine

(2S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-3-nitro-phenyl)-propionic acid

N^α-Boc-(S-p-MeBzl)-D-penicillamine

Downstream raw materials:

<3'-NO2Tyr¹>DPDPE