C₂₅H₃₅N₃O₉

Base Information

• Chemical Name: C₂₅H₃₅N₃O₉
• CAS No.: 1428866-55-0
• Molecular Formula: C₂₅H₃₅N₃O₉
• Molecular Weight: 521.568
• Mol file: 1428866-55-0.mol

Synonyms:

Chemical Property of C₂₅H₃₅N₃O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₅N₃O₉

There total 7 articles about C₂₅H₃₅N₃O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

C25H36N2O7 (1428866-53-8) → C25H35N3O9 (1428866-55-0)

Guidance literature:

With nitric acid; acetic anhydride; acetic acid; at 0 - 20 ℃; for 2.5h;

DOI:10.1021/jm4001693

Reference yield:

(S)-3-n-butylphthalide (3413-15-8) → C25H35N3O9 (1428866-55-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium hydroxide / water; methanol / 0.5 h / 50 °C

1.2: -10 - 0 °C

2.1: dmap; triethylamine / dichloromethane / 5 h / -10 °C

2.2: 1 h / 20 °C / pH 2

3.1: potassium carbonate / acetone / 8 h / 20 °C

4.1: dmap / dichloromethane / 0.17 h / 0 °C

4.2: 8 h / 20 °C

5.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / 2327.23 Torr

6.1: acetic anhydride; acetic acid; nitric acid / 2.5 h / 0 - 20 °C

With dmap; palladium 10% on activated carbon; hydrogen; nitric acid; acetic anhydride; potassium carbonate; acetic acid; triethylamine; sodium hydroxide; In methanol; dichloromethane; water; acetone;

DOI:10.1021/jm4001693

Reference yield:

butylphthalide (3413-15-8,6066-49-5,93133-67-6,125412-70-6) → C25H35N3O9 (1428866-55-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium hydroxide / water; methanol / 0.5 h / 50 °C

1.2: -10 - 0 °C

1.3: -20 - -10 °C

2.1: sodium hydroxide / water; methanol / 0.5 h / 50 °C

2.2: -10 - 0 °C

3.1: dmap; triethylamine / dichloromethane / 5 h / -10 °C

3.2: 1 h / 20 °C / pH 2

4.1: potassium carbonate / acetone / 8 h / 20 °C

5.1: dmap / dichloromethane / 0.17 h / 0 °C

5.2: 8 h / 20 °C

6.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / 2327.23 Torr

7.1: acetic anhydride; acetic acid; nitric acid / 2.5 h / 0 - 20 °C

With dmap; palladium 10% on activated carbon; hydrogen; nitric acid; acetic anhydride; potassium carbonate; acetic acid; triethylamine; sodium hydroxide; In methanol; dichloromethane; water; acetone;

DOI:10.1021/jm4001693

upstream raw materials:

C₁₉H₂₈N₂O₄

2-{2-[(S)-(+)-1-(2-(4-methylpiperazin-1-yl)acetoxy)]pentyl}benzoate-5-benzyloxy-1,4:3,6-dianhydro-D-glucitol

C₂₅H₃₆N₂O₇

(S)-3-n-butylphthalide