Technology Process of C33H35FO4
There total 5 articles about C33H35FO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
caesium carbonate;
In
dimethyl sulfoxide;
at 23 ℃;
for 16h;
Inert atmosphere;
DOI:10.1021/ml300427u
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / 0.37 h / -78 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: hydrogen; palladium 10% on activated carbon / methanol / 24 h / Inert atmosphere
3.1: OJ column / hexane; isopropyl alcohol / Resolution of racemate; Inert atmosphere
4.1: caesium carbonate / dimethyl sulfoxide / 16 h / 23 °C / Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; caesium carbonate; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; hexane; dimethyl sulfoxide; isopropyl alcohol;
DOI:10.1021/ml300427u
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 23 h / 20 °C / Inert atmosphere
2.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / 0.37 h / -78 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
3.1: hydrogen; palladium 10% on activated carbon / methanol / 24 h / Inert atmosphere
4.1: OJ column / hexane; isopropyl alcohol / Resolution of racemate; Inert atmosphere
5.1: caesium carbonate / dimethyl sulfoxide / 16 h / 23 °C / Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; caesium carbonate; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; hexane; dimethyl sulfoxide; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/ml300427u
