C₃₈H₄₃N₃O₆

Base Information

• Chemical Name: C₃₈H₄₃N₃O₆
• CAS No.: 1383737-84-5
• Molecular Formula: C₃₈H₄₃N₃O₆
• Molecular Weight: 637.776
• Mol file: 1383737-84-5.mol

Synonyms:

Chemical Property of C₃₈H₄₃N₃O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₈H₄₃N₃O₆

There total 6 articles about C₃₈H₄₃N₃O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(N-(4-methoxyphenyl)hydrazono)acetate (545445-35-0) + C27H32N2O5 (1383737-79-8) → C38H43N3O6 (1383737-84-5)

Guidance literature:

ethyl 2-(N-(4-methoxyphenyl)hydrazono)acetate; C₂₇H₃₂N₂O₅; With potassium tert-butylate; In tetrahydrofuran; at -78 ℃;

With trifluoroacetic acid; at -78 ℃; for 2h;

DOI:10.1016/j.bmcl.2012.04.106

Reference yield:

C12H13IO4 (1383737-72-1) → C38H43N3O6 (1383737-84-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 2,6-dimethylpyridine; HATU / tetrahydrofuran; N,N-dimethyl-formamide / 1 h / 20 °C

2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tri-n-octylsilane; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 70 °C

3.1: potassium tert-butylate / tetrahydrofuran / 3 h / 20 °C

4.1: dmap; acetic anhydride / tetrahydrofuran / 0.5 h / 20 °C

4.2: 16 h / 20 °C

5.1: potassium tert-butylate / tetrahydrofuran / -78 °C

5.2: 2 h / -78 °C

With 2,6-dimethylpyridine; dmap; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tri-n-octylsilane; potassium tert-butylate; acetic anhydride; N-ethyl-N,N-diisopropylamine; HATU; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.04.106

Reference yield:

C21H22INO3 (1383737-73-2) → C38H43N3O6 (1383737-84-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tri-n-octylsilane; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 70 °C

2.1: potassium tert-butylate / tetrahydrofuran / 3 h / 20 °C

3.1: dmap; acetic anhydride / tetrahydrofuran / 0.5 h / 20 °C

3.2: 16 h / 20 °C

4.1: potassium tert-butylate / tetrahydrofuran / -78 °C

4.2: 2 h / -78 °C

With dmap; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tri-n-octylsilane; potassium tert-butylate; acetic anhydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.04.106

upstream raw materials:

ethyl 2-(N-(4-methoxyphenyl)hydrazono)acetate

C₂₇H₃₂N₂O₅

C₁₂H₁₃IO₄

C₂₁H₂₂INO₃

Downstream raw materials:

C₃₄H₃₅N₃O₆