545445-35-0

Usage

Uses

Used in Pharmaceutical Industry:
[(4-Methoxyphenyl)hydrazono]acetic acid ethyl ester is used as a pharmaceutical agent for its potential anti-inflammatory and analgesic properties. It is being studied for its ability to alleviate pain and reduce inflammation, making it a promising candidate for the development of new medications.
Used in Agrochemical Industry:
In the agrochemical industry, [(4-Methoxyphenyl)hydrazono]acetic acid ethyl ester is used as a chemical intermediate for the synthesis of various agrochemical products. Its versatility in organic synthesis allows for the creation of compounds with potential applications in pest control and crop protection.
Used in Antimicrobial Applications:
[(4-Methoxyphenyl)hydrazono]acetic acid ethyl ester is also being investigated for its antimicrobial properties. It has the potential to be used as an antimicrobial agent, helping to combat bacterial and fungal infections.
Used in Anticancer Applications:
Furthermore, [(4-Methoxyphenyl)hydrazono]acetic acid ethyl ester is being explored for its potential anticancer properties. It may be utilized in the development of novel anticancer drugs, targeting various types of cancer cells and contributing to advancements in cancer treatment.
Overall, [(4-Methoxyphenyl)hydrazono]acetic acid ethyl ester is a versatile and promising compound with a wide range of potential applications in various fields of chemistry and biology, including pharmaceuticals, agrochemicals, antimicrobial, and anticancer research.

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 18794-95-1 3-oxo-2-(2-(4-methoxyphenyl)hydrazono)butanoic acid ethyl ester 
• 79000-20-7 C₁₈H₁₈N₂O₄ 
• 1268701-41-2 ethyl 3-hydroxy-2-(p-methoxyphenylhydrazono)butyrate 
• 1268701-31-0 ethyl 3-hydroxy-2-p-methoxyphenylhydrazono-3-phenylpropionate 

Downstream Products

• 1383737-84-5 C₃₈H₄₃N₃O₆ 
• 1421357-45-0 ethyl 5-(2-methoxy-2-oxoethyl)-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate 
• 1421357-51-8 ethyl 5-[2-(tert-butoxy)-2-oxoethyl]-1-(4-methoxyphenyl)-1Hpyrazole-3-carboxylate 
• 1421357-52-9 ethyl 5-[2-(benzyloxy)-2-oxoethyl]-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate 
• 1421357-53-0 ethyl 5-(2-methoxy-2-oxoethyl)-1-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylate 
• 1421357-55-2 ethyl 5-[2-(benzyloxy)-2-oxoethyl]-1-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylate 
• 1421357-56-3 ethyl 5-(2-(benzyloxy)-2-oxoethyl)-4-ethyl-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate 
• 1421357-62-1 C₁₆H₁₇⁽²⁾HN₂O₅ 
• 1421357-68-7 C₂₂H₃₃⁽²⁾HN₂O₆Si 
• 1421357-69-8 C₂₂H₃₃⁽²⁾HN₂O₆Si 
• 1421357-67-6 C₂₃H₃₅⁽²⁾HN₂O₆Si 
• 1421357-63-2 C₁₇H₁₉⁽²⁾HN₂O₅ 
• 1421357-64-3 (Z)-6-ethyl 1-methyl 3-[(tert-butyldimethylsilyl)oxy]-5-[(E)-(4-methoxyphenyl)diazenyl]-4-methylhex-2-enedioate 
• 1421357-60-9 6-ethyl (2Z,5E)-1-methyl 3-[(tert-butyldimethylsilyl)oxy]-5-[2-(4-methoxyphenyl)hydrazono]hex-2-enedioate 

Relevant academic research and scientific papers

Pyrrolo[3,4-c]pyrazole Synthesis via Copper(?) Chloride-Catalyzed Oxidative Coupling of Hydrazones to Maleimides

A variety of pyrrolo[3,4-c]pyrazole derivatives from readily available aldehyde hydrazones and maleimides via direct oxidative coupling under radical cascade reaction have been reported. This method offers satisfactory chemical yields and good functional

Method for preparing drug Apixaban for preventing or treating venous thrombus after joint replacement

The invention discloses a method for preparing a drug Apixaban for preventing or treating venous thrombus after joint replacement. The method comprises the steps as follows: 1) p-tolylhydrazine and ethyl glyoxylate are subjected to a reaction by catalysis of cuprous bromide in the presence of an alkali and are filtered after the reaction is completed, a borane-methyl sulfide complex is added to a filtrate, a compound shown as the formula I is then added for stirred and mixed reaction, and a reaction mixture L is obtained; 2) the reaction mixture L obtained in the step 1) is stirred under the acidic condition; 3) 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidine-1-yl 3)phenyl]-4,5,6,7-tetrahydro-1H-pyrazole[3,4-c]pyridine-3-carboxylate in the step 1) is subjected to ammonolysis, and Apixaban with the formula shown in the specification is obtained. The method for preparing Apixaban has the advantages of mild condition and higher yield, a pyrazole ring product is generated with a one-pot method, the process is easier, the cost is greatly reduced, and the diazo-reaction widely adopted in the prior art is avoided.

Silver(I)-Catalyzed Tandem Sigamatropic Rearrangement/1,3-H Shift/6π Aza-electrocyclization of N-Propargylic Hydrazones: A Mild Synthetic Route to 1,6-Dihydropyridazines

A highly efficient AgOTf catalyzed [3,3] sigmatropic rearrangement/1,3-H shift/6' aza-electrocyclization cascade reaction of N-propargylic hydrazones has been developed. This method provides a new mild synthetic route to various polysubstituted 1,6-dihydr

Palladium and Copper Cocatalyzed Intermolecular Cyclization Reaction: Synthesis of 5-Aminopyrazole Derivatives

A novel and efficient palladium and copper co-catalyzed intermolecular cyclization of acetonitriles with hydrazones has been developed for the synthesis of 5-aminopyrazoles through C-C and C-N bond formation. The reaction has the advantages of easily avai

Vinylogous reactivity of enol diazoacetates with donor-acceptor substituted hydrazones. Synthesis of substituted pyrazole derivatives

A regiospecific synthesis of multifunctional pyrazoleshas been developed from a cascade process triggered by Rh(II)-catalyzed dinitrogen extrusion from enol diazoacetates with vinylogous nucleophilic addition followed by Lewis acid catalyzed cyclization a

Catalytic asymmetric construction of chiral hydropyridazines via conjugate addition of N-monosubstituted hydrazones to enones

The first example of a highly enantioselective and scalable formal diaza-ene reaction between N-monosubstituted hydrazones and enones catalyzed by a simple chiral primary-second diamine salt has been developed. The catalytic process provides a highly prac

Pyrolysis of 3-hydroxy-2-arylhydrazonoalkanoic acid derivatives

1,2-Diaza-1,3-butadienes have been obtained from readily available 3-hydroxy-2-arylhydrazonopropanoates under various reaction conditions including pyrolysis, dehydration under Mitsunobu conditions or with acetic anhydride or acetic acid. According to their method of synthesis these 1,2-diaza-1,3- butadienes underwent subsequent reactions to give interesting products, and in the presence of proper dienophiles gave the corresponding cycloaddition products. Also, a new approach to pyrazole-3-carboxylic acid derivatives was discovered during an attempt to dehydrate 3-hydroxy-2-arylhydrazonobutanoic esters.