3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate

Base Information

• Chemical Name: 3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate
• CAS No.: 135625-83-1
• Molecular Formula: C₇H₈O₃S*C₇H₁₃NO
• Molecular Weight: 299.391
• Mol file: 135625-83-1.mol

Synonyms:

Chemical Property of 3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate

There total 2 articles about 3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-methoxy-1-methyl-1,2,5,6-tetrahydropyridine (98435-42-8) + toluene-4-sulfonic acid (104-15-4) → 3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate (135625-83-1)

Guidance literature:

In acetone; for 0.25h; educt toluene-p-sulphonic acid: anhydrous;

Reference yield: 31.0%

3-methoxy-1-methyl-1,2,5,6-tetrahydropyridine (98435-42-8) + toluene-4-sulfonic acid (104-15-4) → 1-methyl-3-oxopiperidinium toluene-p-sulphonate (135625-66-0) + 3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate (135625-83-1)

Guidance literature:

In acetone; for 0.25h; educt toluene-p-sulphonic acid: monohydrate;

Reference yield:

3-methoxy-1-methyl-1,2,5,6-tetrahydropyridinium toluene-p-sulphonate (135625-83-1) → 1-methyl-3-methylsulphonylpiperidinium chloride (135625-99-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) HCl / 1) CH₂Cl₂, 5 min; 2) 18 h

2: NaBH₄ / methanol / 24 h

3: 88 percent / HCl / diethyl ether / 2 h / Ambient temperature

4: 57 percent / NaIO₄ / ethanol; H₂O / 24 h / NaIO₄: 2 mol equiv.

With hydrogenchloride; sodium tetrahydroborate; sodium periodate; In methanol; diethyl ether; ethanol; water;

upstream raw materials:

3-methoxy-1-methyl-1,2,5,6-tetrahydropyridine

toluene-4-sulfonic acid

Downstream raw materials:

1-methyl-3,3-bis-(methylsulphenyl)piperidinium toluene-p-sulphonate

3,3-Bis-ethylsulfanyl-1-methyl-piperidine; compound with toluene-4-sulfonic acid

1-methyl-3-methylsulphinylpiperidinium chloride

1-methyl-3-methylsulphonylpiperidinium chloride