<1-¹³C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester>

Base Information

• Chemical Name: <1-¹³C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester>
• CAS No.: 75212-20-3
• Molecular Formula: C₁₂H₁₆O₃S
• Molecular Weight: 241.312
• Mol file: 75212-20-3.mol

Synonyms:

Chemical Property of <1-¹³C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester>

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <1-¹³C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester>

There total 8 articles about <1-¹³C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[α-13C]-benzyl alcohol (54522-91-7) → <1-13C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester> (75212-20-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 65 percent / SOCl₂ / 2 h / Heating

2: 1.) Mg-chips / 1.) ether, 30 min, reflux, 2.) ether, 12 h, reflux

3: 97 percent / 2 N H₂SO₄ / 0.17 h / Heating

4: 58 percent / NaCOOCH₃ / ethanol / 0.5 h / Ambient temperature

5: 60 percent / SOCl₂ / 72 h / 70 °C

6: 1 h / 245 °C / ¹³C-distribution

With thionyl chloride; sulfuric acid; sodium acetate; magnesium; In ethanol;

Reference yield:

<α-13C>Benzylchlorid (57742-41-3) → <1-13C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester> (75212-20-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) Mg-chips / 1.) ether, 30 min, reflux, 2.) ether, 12 h, reflux

2: 97 percent / 2 N H₂SO₄ / 0.17 h / Heating

3: 58 percent / NaCOOCH₃ / ethanol / 0.5 h / Ambient temperature

4: 60 percent / SOCl₂ / 72 h / 70 °C

5: 1 h / 245 °C / ¹³C-distribution

With thionyl chloride; sulfuric acid; sodium acetate; magnesium; In ethanol;

Reference yield:

1-(13C)benzoic acid (3880-99-7) → <1-13C>Phenylthioessigsaeure-O-<2-(2-hydroxyethoxy)ethylester> (75212-20-3)

Guidance literature:

Multi-step reaction with 8 steps

1: 97 percent / diethyl ether; methanol; H₂O

2: 96 percent / LiAlH₄ / diethyl ether / 2 h / Heating

3: 65 percent / SOCl₂ / 2 h / Heating

4: 1.) Mg-chips / 1.) ether, 30 min, reflux, 2.) ether, 12 h, reflux

5: 97 percent / 2 N H₂SO₄ / 0.17 h / Heating

6: 58 percent / NaCOOCH₃ / ethanol / 0.5 h / Ambient temperature

7: 60 percent / SOCl₂ / 72 h / 70 °C

8: 1 h / 245 °C / ¹³C-distribution

With lithium aluminium tetrahydride; thionyl chloride; sulfuric acid; sodium acetate; magnesium; In methanol; diethyl ether; ethanol; water;

upstream raw materials:

5-Phenyl-<5-¹³C>-1,2,3-thiadiazol

diethylene glycol

[α-13C]-benzyl alcohol

<α-¹³C>Benzylchlorid