(+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

Base Information

Chemical Name:(+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole
CAS No.:134276-97-4
Molecular Formula:C₄₃H₄₅NO₈
Molecular Weight:703.832
Hs Code.:

(+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

Synonyms:

Suppliers and Price of (+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

There total 1 articles about (+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133056-49-2
(+)-(4S,5S)-4-(Methoxymethyl)-5-phenyl-2-(1,4,5-trimethoxy-2-naphthyl)-4,5-dihydroxooxazole

: 134276-85-0
2-(3-benzyloxy-2-bromo-5-methoxyphenyl)-5,5-dimethyl-1,3-dioxane

: 133056-52-7
(+)-(4S,5S)-2-(1-hydroxy-4,5-dimethoxy-2-naphthyl)-4-(methoxymethyl)-5-phenyl-4,5-dihydrooxazole

: 134276-97-4,134276-98-5
(+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

Guidance literature:: With magnesium; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, 2) THF, 20h, reflux;

Reference yield:

: 134276-97-4,134276-98-5
(+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

: 134276-91-8,139164-65-1
(-)-(S,1S)-N-<2-<3-hydroxy-2-(4,5-dimethoxy-2-methyl-1-naphthyl)-5-methoxyphenyl>-1-methylethyl>acetamide

Guidance literature:: Multi-step reaction with 10 steps

1: nitromethane / 60 °C

2: potassium hydroxide, water / dimethylsulfoxide / 100 °C

3: 82 percent / potassium carbonate / dimethylformamide / Ambient temperature

4: 97 percent / lithium aluminium hydride / tetrahydrofuran / Ambient temperature

6: 93 percent / ammonium acetate / acetic acid / 2.5 h / 80 °C

7: 1) lithium aluminium hydride, 2) 2-hydroxypyridine / 1) THF, 2h, reflux, 2) toluene, 24h, reflux

8: sulphuric acid / dioxane / 7 h / 90 °C

9: 71 percent / pyridine / 2 h / Ambient temperature

10: 98 percent / hydrogen, conc. hydrochloric acid / palladium/charcoal (10percent) / ethyl acetate

With pyridine; 2-hydroxypyridin; ammonium acetate; hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; sulfuric acid; water; hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; nitromethane; acetic acid; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 134276-97-4,134276-98-5
(+)-(R,4S,5S)-4,5-dihydro-2-<1-<6-benzyloxy-4-methoxy-2-(5,5-dimethyl-1,3-dioxan-2-yl)phenyl>-4,5-dimethoxy-2-naphthyl>-4-methoxymethyl-5-phenyloxazole

: 134276-91-8,139164-65-1
(-)-(S,1R)-N-<2-<3-hydroxy-2-(4,5-dimethoxy-2-methyl-1-naphthyl)-5-methoxyphenyl>-1-methylethyl>acetamide

Guidance literature:: Multi-step reaction with 10 steps

1: nitromethane / 60 °C

2: potassium hydroxide, water / dimethylsulfoxide / 100 °C

3: 82 percent / potassium carbonate / dimethylformamide / Ambient temperature

4: 97 percent / lithium aluminium hydride / tetrahydrofuran / Ambient temperature

6: 93 percent / ammonium acetate / acetic acid / 2.5 h / 80 °C

7: 1) lithium aluminium hydride, 2) 2-hydroxypyridine / 1) THF, 2h, reflux, 2) toluene, 24h, reflux

8: sulphuric acid / dioxane / 7 h / 90 °C

9: 68 percent / pyridine / 2 h / Ambient temperature

10: 97 percent / hydrogen, conc. hydrochloric acid / palladium/charcoal (10percent) / ethyl acetate

With pyridine; 2-hydroxypyridin; ammonium acetate; hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; sulfuric acid; water; hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; nitromethane; acetic acid; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;